The vase life of a flower is determined by a variety of factors, including the type of flower, the environment in which it is kept, and the care it receives. The environment in which a flower is kept can also affect its vase life. Two separated experiments were established for examining the efficacy of calcium nanoparticles (CaNPs) intermixed with or without salicylic acid (SA) at different treatments (Control, CaNPs  2 mM, CaNPs-SA 1 mM, and CaNPs-SA 2 mM), as holding solutions on the vase life and postharvest attributes of Rosa hybrida cv. Black Magic cut flowers. The investigation mentioned the influences of CaNPs-SA on some physiological characteristics in roses, including (vase life, flower diameter, relative fresh weight%, flower stem bending index, and water relations). In addition, total phenol content, membrane stability index (MSI), catalase (CAT) antioxidant activity, and cell wall degrading enzymes (CWDAs) such as xylanase (XYL), polygalacturonase (PG), pectinase (PT), and cellulase (CEL) were determined during 10 days of vase life. As well as the generation rates of H₂O₂, malondialdehyde (MDA), and reduction of DPPH. CaNPs-SA at 2 mM prolonged the vase life and maintained higher relative fresh weight % and water relations. In addition, this superior treatment suppressed the CWDAs, and MDA by promoting the DPPH, and CAT, which increased the MSI of rose-cut flowers. Our study recommends the usage of calcium nanoparticles intermixed with salicylic acid as holding solutions on the vase life and postharvest attributes of Rosa hybrida.