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Comparative Study between the Effect of Marjoram (Origanum marjoram) and Ginger (Zingiber officinale) Extract on the Fertility of Diabetic Male Albino Rats

Article

Last updated: 30 Dec 2024

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Abstract

This research was applied to assess the impacts of marjoram (Origanum marjoram) and ginger (Zingiber officinale) water extract on diabetic male rats' fertility. A total of forty eight Sprague Dawley albino rats allocated into eight groups were utilized in this research. Varying doses of the extract 100, 200 and 400 mg/kg b.w) Body weight (were utilized. Weight of testis, histological study, hormonal assay and sperm analysis were studied. Findings of marjoram and ginger demonstrated no significant change in weight of testis except at the high level, inhibition of testicular tissue peroxidation, improve testosterone (T) levels, parameters of sperm analysis such as sperm concentration and motility than the controls. Elevated serum leptin, and prolactin (PRL) with declined serum T and rise in aromatase action in testis, of the positive controls were observed than negative controls. While, diabetic rats received tested extract showed significantly decreased in leptin, prolactin and aromatase with increasing serum T. Histopathological changes, involving seminiferous tubules (ST) degeneration, with vacuolization, sloughing and decline of spermatogenic cells were also observed in controls. Orally marjoram (ME) or ginger extract (GE), with diabetic rats appeared to avoid these changes by decreased accumulated testicular lipid, increased sperm count and androgens, as well as improve testicular structure. So, this research recommends that intake of marjoram and ginger as a drink or add it to any other food product   ) Such as) had a positive impact on the fertility potentials of the diabetic male rats.

DOI

10.21608/jfds.2023.180204.1087

Keywords

Marjoram and Zingiber, Diabetic male, antioxidant, fertility, histopathology

Authors

First Name

Hayam

Last Name

Elsawy

MiddleName

A.

Affiliation

Department of Special Food and Nutrition, Food Technology Research Institute, Agricultural Research Center, Ministry of Agriculture Land Reclamation, Giza, Egypt

Email

elsawyhayam@yahoo.com

City

-

Orcid

-

First Name

Eman

Last Name

Fouad

MiddleName

A.

Affiliation

Home Economics Dept., Faculty of Specific Education, Mansoura University.

Email

emanfouad179@gmail.com

City

-

Orcid

-

First Name

mahasen

Last Name

kotb

MiddleName

A.

Affiliation

Home Economics Dept., Faculty of Specific Education, Mansoura University.

Email

mahasenali07@gmail.com

City

-

Orcid

-

Volume

14

Article Issue

1

Related Issue

38705

Issue Date

2023-01-01

Receive Date

2023-01-24

Publish Date

2023-01-01

Page Start

13

Page End

24

Print ISSN

2090-3650

Online ISSN

2090-3731

Link

https://jfds.journals.ekb.eg/article_281837.html

Detail API

https://jfds.journals.ekb.eg/service?article_code=281837

Order

3

Type

Original Article

Type Code

886

Publication Type

Journal

Publication Title

Journal of Food and Dairy Sciences

Publication Link

https://jfds.journals.ekb.eg/

MainTitle

Comparative Study between the Effect of Marjoram (Origanum marjoram) and Ginger (Zingiber officinale) Extract on the Fertility of Diabetic Male Albino Rats

Details

Type

Article

Created At

30 Dec 2024