Background: Colorectal cancer (CRC) is the third most common cancer. In Africa, colorectal cancer incidence is 5.7% with slightly higher female incidence, while worldwide it is higher in men. CRC incidence is higher in high socioeconomic people due to changes in lifestyle, so incidence in developed countries is higher than in Africa, especially rural populations. Aim: The aim is to prove epidemiology and clinical data of CRC in the rural population. Materials& Methods: Our study was conducted in Beni-Suef, Egypt. The data was collected from 2017 to the end of 2021. 199 patients had CRC. Gender, age, site, presentation, staging, family history, special habits and histopathology were get. Results: Colorectal cancer accounted for 6.1% of all newly diagnosed cancer patients with 2.6/100.000 population and ranked the sixth common malignancy. The median age was 48.5 years for females and 40 for males with range (19 to 75 years). The incidence was slightly higher in the female with female to male ratio is 1.18:1. Stage 3 was the most common stage (48.2%) and constipation was the most frequent presentation (34%). About one-third of patients were diagnosed younger than 40 years. In males, rectal was the most common side, while the left side was the most common in females. Conclusion: CRC incidence is lower than in developed countries and more common in females than males while in developed countries male incidence is higher. A more advanced stage is found, also a higher young age incidence of CRC in the rural population.