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399583

Phenotypic and Genotypic Characterization of Malassezia Species Isolated from Malassezia Associated Skin Diseases: review article

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Microbiology

Abstract

Lipophilic yeasts called Malassezia are naturally occurring in the skin flora of 75%–98% of healthy adults. They live in areas of the skin that are highly rich with sebaceous glands. The genus Malassezia consists of 22 species They are also the cause of some skin-related diseases, such as: Pityriasis versicolor (PV), seborrheic dermatitis(SD), atopic dermatitis(AD), dandruff and complicated systemic fungal infections, particularly in infants and kids with impaired immune system. Since Malassezia species are dimorphic fungi, their transformation from the yeast to the mould phase allows them to invade the stratum corneum and break through corneocytes, which results in pityriasis versicolor . It is a chronic condition characterized by skin pigmentation that is difficult to cure and has high chance of relapse and recurrence. Seborrheic dermatitis (SD) is a common inflammatory dermatosis that can affect children, adolescents and adults of various ethnicities and races. Since Malassezia species have similar morphological and biochemical characteristics, pityriasis versicolor cannot usually be accurately and quickly diagnosed with the phenotypic approaches currently in use. Consequently, a number of genetic typing methods have been effectively applied, resulting in the identification and classification of new Malassezia species. Molecular techniques such as DNA sequence analysis, restriction fragment length polymorphism (RFLP), random amplified polymorphic DNA (RAPD), and pulsed field gel electrophoresis (PFGE) are used in genotypic identification.This review aims for phenotypic and genotypic identification of Malassezia and Malassezia species.Also aims for antifungal susceptibility testing for Malassezia species by disc diffusion method.

DOI

10.21608/smj.2024.340768.1515

Keywords

Malassezia, lipophilic, Pitryasis versicolor, Phenotypic, genotypic

Authors

First Name

Mai

Last Name

Abo zaid

MiddleName

Mohamed

Affiliation

department of microbiology ,Faculty of medicine, Sohag university, Sohag , Egypt

Email

maiyossef94@gmail.com

City

-

Orcid

-

First Name

abeer

Last Name

mohamed

MiddleName

shneef

Affiliation

Department of Medical Microbiology and Immunology, Sohag Faculty of Medicine, Sohag University

Email

dr_ab_sh@yahoo.com

City

-

Orcid

-

First Name

Reham

Last Name

AlSharkawy

MiddleName

Ezz ElDawla

Affiliation

Department of Dermatology,Venerology& Andrology, Faculty of medicine, Sohag University

Email

reham_elsharkawy@med.sohag.edu.eg

City

-

Orcid

-

First Name

Nesma

Last Name

Hassan

MiddleName

Atef

Affiliation

Department of Medical Microbiology and Immunology, Faculty of Medicine, Sohag University.

Email

nesmaaateef@med.sohag.edu.eg

City

Sohag

Orcid

-

Volume

29

Article Issue

1.

Related Issue

51283

Issue Date

2025-01-01

Receive Date

2024-12-01

Publish Date

2025-01-01

Page Start

24

Page End

29

Print ISSN

1687-8353

Online ISSN

2682-4159

Link

https://smj.journals.ekb.eg/article_399583.html

Detail API

https://smj.journals.ekb.eg/service?article_code=399583

Order

399,583

Type

Review Article

Type Code

2,807

Publication Type

Journal

Publication Title

Sohag Medical Journal

Publication Link

https://smj.journals.ekb.eg/

MainTitle

Phenotypic and Genotypic Characterization of Malassezia Species Isolated from Malassezia Associated Skin Diseases: review article

Details

Type

Article

Created At

30 Dec 2024