Two field experiments were carried out at El-Serw Agricultural Research Station, (latitude of 31.25° N and longitude of 33.49°E), Damietta governorate, Egypt in 2020/2021 and 2021/2022 growing winter seasons. A Randomized Complete Blocks Design (RCBD) arrangement split-plot with three replications was using. Were three sugar beet varieties (Gloria, Laila and Keliopatra) which were randomly in the main plots, while six different herbicides treatments were located in sub-plots randomly (Goltix plus 50% SC at the rate of 1.5 L /feddan (feddan = 4200 m² = 0.420 hectares = 1.037 acres) after 30 days from sowing, Goltix 70% SC at the rate of 2.0 L /feddan pre- sowing, Tegro 27.4% EC at rate 1.0 L /feddan after 30 days from sowing, Giako 10.8% EC at rate 450 cm3 /feddan after 30 days from sowing, hand hoeing thrice at were carried out at three at different times 15, 30 and 45 days after sowing and unweeded treatment "control"). The results showed that sugar beet varieties differed significantly in all studied traits. Laila variety was superior in root length, diameter, number of leaf /plant and (root, top fresh weight and sugar yields /feddan) as well as quality parameters in both seasons compared with other varieties. Gloria and Laila varieties decreased dry at three at different times weight grassy, broad-leaved and total weeds in both seasons. Hand hoeing thrice, Goltix and Goltix plus were give the highest decreased in (dry weight of grassy, broad-leaved and total weeds) and increase in (root fresh weight/plant, foliage fresh weight/plant and No. leaves/plant, top fresh weight, root yield and sugar yield /feddan) as well as quality parameters compared with unweeded treatment in both seasons. Under conditions of the present study, planting Gloria variety of sugar beet, with Hand hoeing thrice and/or using Tegro 27.4% EC herbicide at rate 1.0 L /feddan after 30 days from sowing can tribute to achieving significantly higher roots and sugar yields compared with unweeded treatment (control).