The current study aims to rationalize the use of nitrogen fertilizer by using alternatives of biological and organic fertilizers and their interactions on cucumber crop productivity and quality. The experimental design was split split plot design with three replicates. Cucumber plants was tested under two bio-fertilizations (with and without), four types of compost (without, plant, animal and mixed compost) as well as three rates of mineral-N i.e., (25, 50, and 75 kg/feddan) (feddan = 4200 m²). The main effect of biological, organic and N fertilization compared to non-fertilized showed a significant increase in cucumber yield, all crop components, and the percentage of TSS in cucumber fruits, in both seasons. Results indicated that the increase in cucumber crop productivity was estimated at (13.04%, 11.42%), (17.89%, 38.04%) and (43.83%, 55.69%) as a result of biological, organic and nitrogen fertilization in both seasons, respectively. Despite the superiority of the intervention treatment containing 4 ton/feddan, (mixed compost) + (mixed bio) + Mineral-N at a rate of 75 kg/feddan.  Statistical analysis proved to apply 4 ton/feddan of (mixed compost) + (mixed bio) + Mineral-N at a rate of 50 kg/feddan, because there is no significant difference with mineral-N fertilization treatment.