The current study aimed to determine the status of strategic leadership practice in terms of strategic direction, developing human capital, enhancing organizational culture ethical practices within university youth welfare agencies. Furthermore, it sought to describe the status of institutional performance in university youth welfare agencies, determine the nature of the relationship between the level of strategic leadership practice and institutional performance in university youth welfare agencies, and propose mechanisms to improve institutional performance. A descriptive study used comprehensive social survey tool for (104) employees of the university youth welfare agencies at Fayoum University. The results of the study revealed that there is a statistically significant positive correlation between the level of strategic leadership practice- which includes strategic direction, developing human capital, promoting organizational culture, ethical practices- and institutional performance in university youth welfare agencies. The study recommended the need to monitor external environmental changes and develop information and communication systems to improve the performance of university youth welfare agencies, and continuous follow-up of employee performance and continuous benchmarking to improve Institutional Performance in university youth welfare agencies.