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384500

Pharmacological Potentials of the Genus Coccoloba and Its Phytochemical Constituents: An Updated Review Since 2020

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

Genus Coccoloba is the third largest genus among Family Polygonaceae (Knotweed family), comprising about 120 species. Pursuing to our exploration of various Coccoloba species, an updated mini-review about the phytochemical and biological profiling of its species is presented. It covers the scientific literature from 2020 - till now. Various biological activities were verified and assessed, e.g., antiprotozoal, smooth muscle relaxation, immunomodulatory and hepatoprotective. Phytochemical studies disclosed the presence of lignin oligomers, alkaloids and new methylated flavonoids. Some extracts were incorporated in modern pharmaceutical formulations for enhanced stability and permeability. Finally, the review explore the pitfalls of scientific literature investigating Coccoloba species.

DOI

10.21608/ejchem.2024.311546.10181

Keywords

Coccoloba, Phytochemical constituents, Polygonaceae, Hepatoprotective, Smooth muscle relaxant, immunomodulatory activity

Authors

First Name

Fatma

Last Name

Mohamed

MiddleName

Abdelhakim

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Heliopolis University

Email

fatma.abdelhakim@hu.edu.eg

City

-

Orcid

0009-0006-7448-840X

First Name

Mohammed

Last Name

Khalil

MiddleName

N. A.

Affiliation

Pharmacognosy Department, Faulty of Pharmacy, Cairo University

Email

mohamed.nabil@pharma.cu.edu.eg

City

-

Orcid

0000-0002-1134-1164

First Name

Mohamed

Last Name

Salem

MiddleName

A.

Affiliation

Pharmacognosy and natural products chemistry, Faculty of Pharmacy, Menofia University, Egypt

Email

mohamed.salem@phrm.menofia.edu.eg

City

-

Orcid

-

First Name

Amira

Last Name

El Senousy

MiddleName

Safwat

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Cairo University

Email

amira.elsenousy@pharma.cu.edu.eg

City

-

Orcid

-

First Name

Ali

Last Name

El-Halawany

MiddleName

M.

Affiliation

Pharmacognosy department, Faculty of Pharmacy, Cairo University

Email

ali.elhalawany@pharma.cu.edu.eg

City

-

Orcid

-

Volume

67

Article Issue

12

Related Issue

50716

Issue Date

2024-12-01

Receive Date

2024-08-11

Publish Date

2024-12-01

Page Start

203

Page End

216

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 67_Issue 12_Pages 203-216.pdf

PDF . 6.4MB

Link

https://ejchem.journals.ekb.eg/article_384500.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=384500

Order

384,500

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Pharmacological Potentials of the Genus Coccoloba and Its Phytochemical Constituents: An Updated Review Since 2020

Details

Type

Article

Created At

30 Dec 2024