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339776

PHYTOCONSTITUENTS, PHARMACOLOGICAL AND TRADITIONAL USES OF CROCUS SATIVUS Linn.: An UPDATED REVIEW

Article

Last updated: 01 Jan 2025

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Abstract

Crocus sativus Linn., (family- Iridaceae) commonly known as saffron (Kesar), is grown widely in tropical and subtropical regions and is used both in the home and for medicine. Various chemical constituents present in the stigma of Crocus sativus, including crocetin (14), crocin (15), safranal (16) and picrocrocin (17) which are very important volatile and aromatic compounds. The presence of these constituents makes the herb very costly and imparts different medicinal properties to it. Since prehistoric times, saffron is used as a traditional/ herbal medicine in Asian countries. It is reported that Crocus sativus L. has antioxidant, aphrodisiac, antigenotoxic, antiproliferative, anxiolytic, anticonvulsant, antidepressant, antinociceptive, hypotensive, anti-inflammatory and relaxant effects. In this review, a comprehensive detail of the salient features, chemical constituents, and therapeutic uses of C. sativus L. has been highlighted.

DOI

10.21608/ejchem.2024.240039.8710

Keywords

Saffron, Crocetin, Crocus sativus L, Crocin, safranal

Authors

First Name

Adil

Last Name

Wali

MiddleName

Farooq

Affiliation

Department of Pharmaceutical Chemistry, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates

Email

farooq@rakmhsu.ac.ae

City

Ras Al Khaimah

Orcid

0000-0003-1555-2820

First Name

Jayachithra

Last Name

Pillai

MiddleName

Ramakrishna

Affiliation

Department of Pharmaceutical Chemistry, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates

Email

jayachithra@rakmhsu.ac.ae

City

Ras Al Khaimah

Orcid

0000-0002-7365-6786

First Name

Sirajunisa

Last Name

Talath

MiddleName

-

Affiliation

Department of Pharmaceutical Chemistry, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates

Email

sirajunisa@rakmhsu.ac.ae

City

-

Orcid

0000-0002-2334-2332

First Name

Bhoomendra

Last Name

Bhongade

MiddleName

-

Affiliation

Department of Pharmaceutical Chemistry, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates

Email

bhoomendra@rakmhsu.ac.ae

City

Ras Al Khaimah

Orcid

0000-0002-4057-7125

First Name

Rania

Last Name

Ghanem

MiddleName

Hamed

Affiliation

Department of General Education, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates

Email

rania@rakmhsu.ac.ae

City

Ras Al Khaimah

Orcid

0000-0002-3215-355X

Volume

67

Article Issue

8

Related Issue

47534

Issue Date

2024-08-01

Receive Date

2023-10-04

Publish Date

2024-08-01

Page Start

83

Page End

93

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_339776.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=339776

Order

339,776

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

PHYTOCONSTITUENTS, PHARMACOLOGICAL AND TRADITIONAL USES OF CROCUS SATIVUS Linn.: An UPDATED REVIEW

Details

Type

Article

Created At

30 Dec 2024