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340249

Pinuspalustrols A & B, Two Rare Dimeric Abietane-O-O-Abietane-Type Diterpenoids of Natural Colophony from Pinus palustris

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Organic chemistry

Abstract

Pinus palustris' natural colophony produced two novel secondary metabolites, pinuspalustrols A (1) & B (2), a unique pair of C-7 epimeric dimers based on abietane-type diterpenoids linked via C7-C12' peroxy conjunction system. Additionally, their biogenesis-related diterpenoid monomers were previously reported (3-10). Spectroscopic techniques, particularly 1D and 2D NMR together with HREIMS, were used to elucidate their planar structures, while their relative configurations were decided by NOESY spectra, together with comparison with NMR data of known analouges. Both pinuspalustrols A (1) and B (2) possess a skeleton of 12-Hydroxyabieta-8,11,13-trien-7-yl 6-Hydroxy-7-oxoabieta-8,11,13-trien-12-yl peroxide, but they are epimeric at position 7. It is noteworthy that chemical compounds 3-10 were first isolated from P. palustris.

DOI

10.21608/ejchem.2024.260239.9134

Keywords

Colophony, Pinus palustris, Pinaceae, dimeric abietane, diterpenoid

Authors

First Name

Mohamed

Last Name

AbdEl-Razek

MiddleName

H

Affiliation

Chemistry of Natural Compounds Department, Institute of Pharmaceutical and Drug Industries Research, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, P.O. 12622, Egypt

Email

abdelrazek3@yahoo.com

City

Giza

Orcid

0000-0003-0978-8925

First Name

Ahmed

Last Name

Soliman

MiddleName

A.F.

Affiliation

Department of Pharmacognosy, Institute of Pharmaceutical and Drug Industries Research, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, P.O. 12622, Egypt

Email

ashehabeldin2007@yahoo.com

City

Giza

Orcid

-

First Name

Mohamed

Last Name

Aboelmagd

MiddleName

-

Affiliation

Department of Pharmacognosy, Institute of Pharmaceutical and Drug Industries Research, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, P.O. 12622, Egypt

Email

m.magd83@yahoo.com

City

-

Orcid

0000-0003-3527-4872

First Name

Ahmed H.

Last Name

El-Desoky

MiddleName

-

Affiliation

Department of Pharmacognosy, Institute of Pharmaceutical and Drug Industries Research, National Research Centre (NRC), 33 El-Behouth St., Dokki, Giza, P.O. 12622, Egypt

Email

wasseif@yahoo.com

City

-

Orcid

0000-0002-7770-9793

Volume

67

Article Issue

8

Related Issue

47534

Issue Date

2024-08-01

Receive Date

2024-01-02

Publish Date

2024-08-01

Page Start

47

Page End

55

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 67_Issue 8_Pages 47-55.pdf

PDF . 865.6kB

Link

https://ejchem.journals.ekb.eg/article_340249.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=340249

Order

340,249

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Pinuspalustrols A & B, Two Rare Dimeric Abietane-O-O-Abietane-Type Diterpenoids of Natural Colophony from Pinus palustris

Details

Type

Article

Created At

30 Dec 2024