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336252

Phytochemical Profiling of Hippobroma longiflora Leaf Extract Using LC-MS/MS Analysis and Pharmacological Potential

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Last updated: 01 Jan 2025

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Abstract

Hippobroma longiflora is a weed plant with diverse metabolites, including alkaloids, phenolics, tannins, and saponins. The community in several tropical regions uses this plant as medicine, but information about the metabolite profile contained in its leaves is still quite limited. Therefore, this research was conducted to identify the metabolite content in Hippobroma longiflora leaf extract and investigate its potential pharmacological effects to ensure its use in healthcare. The method used was LC-MS/MS, followed by inputting the results of LC-MS/MS into MS Dial and MS Finder applications to identify the essential compounds. The analysis resulted in 29 compounds identified: phenolic, terpenoid, and alkaloid compound groups. Hippobroma longiflora contains several potent antioxidants, antibacterial or antiviral compounds, and anticancers. In conclusion, Hippobroma longiflora leaf extract is rich in compounds that can be utilized by the community in medicine and healthcare, in particular for certain infectious diseases and anticancer.

DOI

10.21608/ejchem.2024.242541.8740

Keywords

secondary metabolites, traditional medicine, weed plant

Authors

First Name

Asril

Last Name

Burhan

MiddleName

-

Affiliation

Department of Biology, Faculty of Mathematics and Natural Sciences, Jalan Agatis-Dramaga Campus, IPB University, Bogor 16680, Indonesia

Email

asrilburhan@gmail.com

City

makassar

Orcid

0000-0002-0391-812X

First Name

Diah

Last Name

Ratnadewi

MiddleName

-

Affiliation

Department of Biology, Faculty of Mathematics and Natural Sciences, Jalan Agatis-Dramaga Campus, IPB University, Bogor 16680, Indonesia

Email

dratnadewi@apps.ipb.ac.id

City

Bogor

Orcid

0000-0003-1638-4742

First Name

Agus

Last Name

Setiyono

MiddleName

-

Affiliation

Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia.

Email

agusse@apps.ipb.ac.id

City

Bogor

Orcid

-

First Name

Rika

Last Name

Astuti

MiddleName

Indri

Affiliation

Department of Biology, Faculty of Mathematics and Natural Sciences, Jalan Agatis-Dramaga Campus, IPB University, Bogor 16680, Indonesia

Email

rikaindriastuti@apps.ipb.ac.id

City

Bogor

Orcid

0000-0003-1561-6943

First Name

Abdul

Last Name

Umar

MiddleName

Halim

Affiliation

College of Pharmaceutical Sciences Makassar, STIFA Makassar, Jalan Perintis Kemerdekaan Km. 13.7 Daya, Makassar 90242, Indonesia

Email

ahuhalim76@yahoo.com

City

Makassar

Orcid

0000-0002-2515-3455

Volume

67

Article Issue

7

Related Issue

47288

Issue Date

2024-07-01

Receive Date

2023-10-14

Publish Date

2024-07-01

Page Start

83

Page End

90

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 67_Issue 7_Pages 83-90.pdf

PDF . 169.8kB

Link

https://ejchem.journals.ekb.eg/article_336252.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=336252

Order

336,252

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Phytochemical Profiling of Hippobroma longiflora Leaf Extract Using LC-MS/MS Analysis and Pharmacological Potential

Details

Type

Article

Created At

30 Dec 2024