This work investigated the ability of maleic acid anhydride grafted cellulose functionalized with thiourea (Cell-THU) to adsorb Cu (II), Mn (II), Cd (II), Fe (III) and Pb (II) ions from aqueous solution. Using a variety of conditions including adsorbent dose, pH, contact time, metal cations concentration and temperature at 500 rpm, the process of adsorption for this produced adsorbent to remove the analyzed metal cations was examined in a batch technique. The mechanism of adsorption process is declared by applying different kinetics and isotherm models. Maximum adsorption capacities for Cu (II), Mn (II), Cd (II), Fe (III) and Pb (II) were 29.85, 25.91, 31.84, 26.18, and 33.22 mg/g, respectively at pH=7, adsorbent dose=0.3 mg/L, contact time=90 min. and initial metal cation concentration (3 mg/L) at room temperature (25°C) . With that maximal adsorption capacity, the Langmuir isotherm produces the best match to the equilibrium data. Data analysis using kinetics revealed that the adsorption related to pseudo 2nd order model. It was observed that Cell-THU performs really well for eliminating toxic metal ions.