Paper-based artworks are susceptible to deterioration over time due to various factors such as exposure to light, humidity, and pollutants. Stains on paper can further accelerate this deterioration process and compromise the integrity of the artwork. This study aims to provide a comprehensive understanding of different methods for stain removal using plasma technology. Plasma treatment involves the use of ionized gas to modify the surface properties of materials. In the context of paper conservation, plasma techniques can be used to selectively remove stains without damaging the underlying paper substrate. These techniques include atmospheric pressure plasma, low-pressure plasma, and cold plasma treatment. Atmospheric pressure plasma is a non-thermal plasma treatment that can effectively remove stains from paper surfaces without causing thermal damage. Low-pressure plasma treatment involves the use of vacuum chambers to create a controlled environment for stain removal. Cold plasma treatment utilizes low temperatures to prevent heat damage to the paper while effectively removing stains. Overall, plasma techniques offer a safe and efficient method for the removal of stains from paper-based artworks, preserving their aesthetic and historical value for future generations.