This research investigates the extent of knowledge and comprehension of the new model of care (MoC) among the staff of the Jeddah First Health Cluster at King Abdulaziz Hospital and its associated facilities in Saudi Arabia. The study seeks to assess the staff's level of knowledge, understanding, willingness to embrace, and preparedness to implement the MoC. A cross-sectional survey was undertaken among healthcare professionals and administrators, with a total of 350 participants who successfully filled out the questionnaire. The results suggest that a significant proportion of participants (53.8%) possess knowledge of the current transformations and advancements in the healthcare industry of Saudi Arabia, while 37% demonstrate a solid comprehension of the MoC concept. However, just a third of the individuals are acquainted with the newly introduced MoC. The findings also indicate that 40.7% of the staff express agreement with the objectives and components of the MoC. However, there is a need to enhance their acceptance and desire to actively participate in its execution. The research offers useful insights for targeted interventions to improve staff comprehension, acceptance, and implementation of the MoC, thereby enhancing the quality of healthcare services in the Jeddah First Health Cluster.