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Nursing Interventions and Biochemical Markers in Early Detection of Neonatal Sepsis

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Biochemistry

Abstract

Aim: This study aims to explore the role of nurses and the use of biochemical markers in the management of neonatal sepsis. Methods: A comprehensive literature review was conducted to analyze current research on the roles of nurses in neonatal sepsis management and the utility of biochemical markers such as C-reactive protein (CRP), procalcitonin (PCT), interleukins (IL-6, IL-8, IL-10), and soluble CD14 subtype presepsin (sCD14-ST) in diagnosing and monitoring neonatal sepsis. Studies focusing on clinical trials, observational studies, and meta-analyses published between 2000 and 2024 were included. Results: Nurses play a critical role in the early recognition and management of neonatal sepsis through vigilant monitoring, timely intervention, and effective communication with healthcare teams. Biochemical markers, particularly CRP and PCT, have shown promise in aiding early diagnosis and monitoring treatment response. IL-6, IL-8, IL-10, and sCD14-ST have also demonstrated potential as adjunctive markers in differentiating sepsis from non-infectious conditions. Conclusion: The integration of nurses in the multidisciplinary care team is crucial for improving outcomes in neonatal sepsis. Biochemical markers provide valuable adjuncts to clinical assessment, facilitating early diagnosis, appropriate antibiotic use, and monitoring of treatment efficacy. Further research is needed to standardize protocols for marker use, optimize diagnostic accuracy, and enhance the overall management of neonatal sepsis.

DOI

10.21608/ejchem.2024.303722.9998

Keywords

Neonatal sepsis, Nurses' Role, Biochemical markers, C-reactive protein, Procalcitonin, Interleukins, soluble CD14 subtype presepsin

Authors

First Name

Nawaf Sharqi Khalaf

Last Name

Alanazi

MiddleName

-

Affiliation

Nursing, Northern Area Armed Forces Hospital. King Khalid Military City, PO Box 10018, Hafr Al Batin 31991 , Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Bandar Sharqi Khalaf

Last Name

Alanazi

MiddleName

-

Affiliation

Nursing, Northern Area Armed Forces Hospital. King Khalid Military City, PO Box 10018, Hafr Al Batin 31991 , Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Khalid Sharqi Khalaf

Last Name

Alanazi

MiddleName

-

Affiliation

Nursing, Northern Area Armed Forces Hospital. King Khalid Military City, PO Box 10018, Hafr Al Batin 31991 , Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Ahmed Ibrahim Mohammed

Last Name

Habadi

MiddleName

-

Affiliation

Nursing technician, Prince Mohammad bin Nasser Hospital in Jazan, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Amnah Aziz

Last Name

Alsubaie

MiddleName

-

Affiliation

Specialist Nursing, Imam Abdul Rahman Al-Faisal Hospital, Riyadh First Health Cluster, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Noora Mohammed

Last Name

Alnaji

MiddleName

-

Affiliation

Specialist Nursing, Baish General Hospital, Jazan 87597, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Fahad Abdu Shoei

Last Name

Humedi

MiddleName

-

Affiliation

Nursing technician, Eradah for mental health Hospital in Jazan, Jazan Cluster, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Ghadah Saud

Last Name

Alanazi

MiddleName

-

Affiliation

Ministry of health, Kingdom of Saudi Arabia 7Epidemiological observer, Compliance Department, Riyadh Health, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Ashwaq Faleh Mater

Last Name

Anzy

MiddleName

-

Affiliation

Ministry of health, Kingdom of Saudi Arabia 7Epidemiological observer, Compliance Department, Riyadh Health, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Atif Ogiby

Last Name

Alkhayri

MiddleName

-

Affiliation

Ministry of health, Kingdom of Saudi Arabia 7Epidemiological observer, Compliance Department, Riyadh Health, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Fatimah Ali

Last Name

Hakami

MiddleName

-

Affiliation

Ministry of health, Kingdom of Saudi Arabia 7Epidemiological observer, Compliance Department, Riyadh Health, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Fahd Nasser

Last Name

Alshakarah

MiddleName

-

Affiliation

Epidemiological observer, Compliance Department, Riyadh Health, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

First Name

Saleh Mohammed

Last Name

Alklywy

MiddleName

-

Affiliation

Ministry of health, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Salhah Ali Ibrahim

Last Name

Saddeg

MiddleName

-

Affiliation

Nursing technician, Primary Health Care Center in Albaidh, Riyadh, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Shrouq Kassim Ahmed

Last Name

Moharram

MiddleName

-

Affiliation

Nursing technician, Riyad, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

Volume

67

Article Issue

13

Related Issue

46555

Issue Date

2024-12-01

Receive Date

2024-07-12

Publish Date

2024-12-01

Page Start

729

Page End

742

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 67_Issue 13_Pages 729-742.pdf

PDF . 500.1kB

Link

https://ejchem.journals.ekb.eg/article_375168.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=375168

Order

375,168

Type

Review Articles

Type Code

444

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Nursing Interventions and Biochemical Markers in Early Detection of Neonatal Sepsis

Details

Type

Article

Created At

30 Dec 2024