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338014

Developing Biodegradable Polymeric Composite for Nails Manufacturing of Bone Fracture Fixation

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Biochemistry

Abstract

Biodegradable implants, a popular research focus, aim to address issues associated with traditional titanium and stainless-steel implants, including bone abnormalities and the need for additional surgeries. Our novel protein-based thermoplastic material, derived from blood albumin, serves as a promising biodegradable implant. Despite inherent weak mechanical properties in biodegradable materials, we enhance our biopolymer by incorporating reinforcing components like Nanoclay, PVA, and PLA. Three composite groups were tested, and various fabrication techniques were explored, revealing that dry casting with pure protein or 20% nanoclay concentration yields the best mechanical properties for bone fixation plates. The tensile strength of the dry casting plate is 8.3 MPa for pure protein. Our results indicate that this novel protein-based material, particularly with dry casting, presents a promising alternative to traditional fixation plate materials for pediatric or maxilla bone fractures with lower load requirements.

DOI

10.21608/ejchem.2024.257443.9038

Keywords

Natural biomaterials, protein-based biomaterials, biodegradable implants

Authors

First Name

Ahmed

Last Name

Yousry

MiddleName

Mohamed

Affiliation

Biomedical Engineering Department, Faculty of Engineering, Helwan University, Helwan, Egypt

Email

ahmed_ahkce@yahoo.com

City

cairo

Orcid

-

First Name

Hassan

Last Name

Mustafa

MiddleName

M. M.

Affiliation

Mechanical Engineering Department, Engineering and Renewable Energy Research Institute, National Research Centre, Giza, Egypt.

Email

hassanabuhashish@gmail.com

City

Dokki

Orcid

0000-0002-1854-0481

First Name

Wael

Last Name

Abdelmoez

MiddleName

-

Affiliation

Chemical Engineering Department, Faculty of Engineering, Minia University, Minia, Egypt

Email

drengwael2003@yahoo.com

City

Minia

Orcid

-

First Name

Mohamed Tarek

Last Name

El-Wakad

MiddleName

-

Affiliation

Faculty of Engineering and Technology, Future University Egypt, Fifth settlement, Cairo, Egypt

Email

mohamed.elwakad@fue.edu.eg

City

cairo

Orcid

-

First Name

Mohamed S.

Last Name

Abdo

MiddleName

-

Affiliation

Biomedical Engineering Department, Faculty of Engineering, Minia University, Minia, Egypt.

Email

bioengmsa@yahoo.com

City

Helwan

Orcid

0000-0001-7044-959X

Volume

67

Article Issue

13

Related Issue

46555

Issue Date

2024-12-01

Receive Date

2023-12-23

Publish Date

2024-12-01

Page Start

349

Page End

359

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_338014.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=338014

Order

338,014

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Developing Biodegradable Polymeric Composite for Nails Manufacturing of Bone Fracture Fixation

Details

Type

Article

Created At

30 Dec 2024