A common issue in many oil and gas fields is the presence of hydrogen sulphide H2S in the hydrocarbon fluids. Unwanted contamination of H2S poses several risks to public health and the environment. It is caustic, offensive, and corrosive. As a result, the industry has long been in need of a technique that can reliably remove H2S from natural gas, or at least lower its level during production, storage, or processing to meet safety and product specification criteria. A common method for eliminating or lowering the concentration of H2S in hydrocarbon production fluids is to inject an H2S scavenger into the hydrocarbon stream. The Egyptian Petroleum Research Institute (EPRI) produces EPRI H2S scavenger, which is one of their compounds. This injection dosage rate is calculated statistically using modeling and simulation of a Zohr Gas field in the Mediterranean Sea as a case study. The project entails the construction of a gas field Zohr, Egypt, with a daily capacity of 850 billion standard cubic meters. The H2S inlet concentration, pipe length, diameter, pressure, and gas flow rate all play a role in determining the ideal H2S scavenger injection dosage rate. Using the software application Lingo, the optimization results are achieved for various values of these parameters. In general, increasing the diameter of the pipe and raising the intake H2S concentration increases the optimal values of the H2S scavenger injection dosage rate for hydrogen sulphide scavenging, whereas increasing the length of the pipe, gas flow rate, and pressure decreases them.