Diuretics are medications utilized to lower blood pressure by enhancing urine production and sodium expulsion. Nevertheless, various diuretics, including loop and thiazide diuretics, can lead to adverse effects such as imbalances in electrolytes. Consequently, there is a growing fascination in exploring the therapeutic attributes of herbs and botanicals. Natural remedies derived from plants are considered a viable option for treating specific conditions and providing protection against certain diseases. Scientific evidence is progressively supporting the diuretic properties of traditional medicinal plants. This article delves into the potential mechanisms underlying these diuretic effects and reviews research that identifies extracts promoting diuresis, measured through urine output, sodium, and potassium excretion. The review highlights various genera and species with well-documented diuretic effects.