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Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack

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Last updated: 01 Jan 2025

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Abstract

Isem kembang (Mangifera quadrifida Jack) is part of the Mangifera clan of the Anacardiaceae tribe. Research on the benefits of ripe Mangifera quadrifida Jack fruit as an antibacterial (antimicrobial) and cytotoxic agent with Brine Shrimp of Lethality Test (BSLT) have been successfully conducted.This research was conducted in two stages, namely the extraction of the ripe fruit flesh of Mangifera quadrifida Jack with the maceration method using n-hexane, ethyl acetate, and methanol, followed by antibacterial testing using the well-diffusion method (disk diffusion assay) and cytotoxicity testing using the Lethality Test of Brine Shrimp. According to the results the extraction of ripe fruit flesh Mangifera quadrifida Jack shows that ethyl acetate is the best solvent for extracting and killing bacteria, the methanol extract of ripe fruit flesh from Mangifera quadrifida Jack has potential as a compound antitumor or anticancer drug as the Brine Shrimp Lethality Test (BSLT) method show acute toxicity to Artemia salina Leach larvae.

DOI

10.21608/ejchem.2023.186779.7440

Keywords

Mangifera quadrifida Jack fruit, Brine Shrimp Lethality Test (BSLT), antibacterial (antimicrobial), cytotoxic agent

Authors

First Name

Rosalina

Last Name

Rosalina

MiddleName

-

Affiliation

Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia

Email

rosalinahasan89@gmail.com

City

Bogor

Orcid

-

First Name

Candra

Last Name

Irawan

MiddleName

-

Affiliation

Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor, Indonesia

Email

candra_irawan@aka.ac.id

City

-

Orcid

0000-0001-9870-6543

First Name

Jenny Anna

Last Name

Tambunan

MiddleName

Margaretta

Affiliation

Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia

Email

jennyevry@gmail.com

City

Bogor

Orcid

-

First Name

Hanafi

Last Name

Hanafi

MiddleName

-

Affiliation

Department of of Food Industrial Quality Assurance, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia

Email

hanafi_ariel@yahoo.com

City

Bogor

Orcid

-

First Name

Andita

Last Name

Utami

MiddleName

-

Affiliation

Department of Analytical Chemistry, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia

Email

anditautami.j@gmail.com

City

Bogor

Orcid

0000-0001-6784-4628

First Name

Dewi

Last Name

NIngsih

MiddleName

Pujo

Affiliation

Department of Analytical Chemistry, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia

Email

dewi-pujo@kemenperin.go.id

City

Bogor

Orcid

-

First Name

Fadilah

Last Name

Fadilah

MiddleName

-

Affiliation

Department of Medical Chemistry, Faculty of Medicine, University of Indonesia, Indonesia

Email

fadilah81@gmail.com

City

-

Orcid

-

Volume

66

Article Issue

13

Related Issue

43707

Issue Date

2023-12-01

Receive Date

2023-01-11

Publish Date

2023-12-01

Page Start

775

Page End

780

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 66_Issue 13_Pages 775-780.pdf

PDF . 349.3kB

Link

https://ejchem.journals.ekb.eg/article_297098.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=297098

Order

297,098

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Manufacturing and Testing the Antibacterial Activity of Cytotoxicity by Lethality Test of Brine Shrimp, Antibacterial Activity of Ripe Fruit Flesh Mangifera quadrifida Jack

Details

Type

Article

Created At

30 Dec 2024