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251877

Evaluation of the antioxidant and Anti-inflammatory Activities of Moringa oleifera Lam Extracts and Determination of Their Active Components

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Biochemistry

Abstract

Background: Natural products are attracting the attention of researchers due to their widespread use in pharmaceutical industries. Moringa oleifera is one of these plants with bioactivity and is used as an antioxidant. Objective: The current research was conducted to assess the anti-inflammatory and antioxidant efficacies of various Moringa leaf extracts and determine their active components. Materials and Methods: Different solvents (cold water, hot water, 70% ethanol, cold ethanol, and hot ethanol) were utilized to extract M. oleifera. The extracts were then analyzed with FTIR to determine the percentage of active compounds in each extract. Stabilization of the red blood cell membrane, denaturation protein inhibition, and antioxidant potential of the extracts were determined. Results: The FTIR analysis revealed the active components in the various extracts to be phenol compounds, as evidenced by a specific peak in certain regions. The hot ethanolic extract was found to have the highest amount of bioactive compound (89.33%) compared to other extracts. Also, the same extract had the highest activity in stabilizing red blood cells, protein inhibition, as well as radical scavenging. Conclusion: The findings of this investigation indicate that the hot ethanolic extract of M. oleifera is more effective in all the test activities compared to the other extracts.

DOI

10.21608/ejchem.2022.147344.6387

Keywords

antioxidant, Moringa oleifera, TPC, Protein denaturation, FTIR, RBCs membrane stabilization

Authors

First Name

Sundus

Last Name

Ahmed

MiddleName

Hameed

Affiliation

College of Science, MUSTANSIRIYAH University, Baghdad, Iraq

Email

sundusha2021@gmail.com

City

-

Orcid

-

First Name

Hadeel

Last Name

Hassan

MiddleName

Esam

Affiliation

Biology Department, College of Science, Mustansiriyah University, Baghdad, Iraq

Email

isamhtk@hotmail.com

City

-

Orcid

-

First Name

Ferial

Last Name

Mahdi

MiddleName

Majed

Affiliation

Veterinary medicines Department, Industrial Research and Development, Ministry of Industry and Minerals

Email

isamhtk@yaoo.com

City

-

Orcid

-

Volume

66

Article Issue

7

Related Issue

42039

Issue Date

2023-07-01

Receive Date

2022-06-29

Publish Date

2023-07-01

Page Start

479

Page End

486

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_251877.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=251877

Order

251,877

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Evaluation of the antioxidant and Anti-inflammatory Activities of Moringa oleifera Lam Extracts and Determination of Their Active Components

Details

Type

Article

Created At

30 Dec 2024