Abstract

A series of new α,β-unsaturated carbonyl compounds , thiophene, imine and coumarin derivatives were synthesized from reaction of hydrazide-hydrazone derivative with different reagents (substituted aromatic ketone, cyclopentanone, cycloheptanone, tetralone, malononitrile, 2-hydroxy-1-benzaldehyde and 2-hydroxy-1-naphthaldehyde) using different conditions. Hydrazide-hydrazone derivative was prepared by the reaction of piperonal with 2-cyanoacetohydrazide under reflux in ethanol. On the basis of their spectral information, the structures of the newly synthesized chemical derivatives were determined.