In our research, organic derivatives were utilized as an eco-friendly green inhibitor to prevent Cu dissolution in 1 M of HNO3. This study was carried out using chemical methods such as mass loss method (ML), potentiodynamic polarization (PP), and impedance (EIS) techniques. The results obtained from these methods showed that with increasing the concentration of these substances and the inhibition efficiency (%IE) increased and reached to 95.1%. The adsorption of these derivatives on the copper (Cu) surface was used to explain the inhibition. The inhibitors were of mixed kind, according to the polarization curves. It was found that these derivatives follow Langmuir adsorption isotherm. Several surface inspection methods (Scanning electron microscope (SEM), EDX and Fourier transform infrared spectroscopy (FT-IR) have been used. It was found that all of these used methods are in agreement with each other.