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Studying the Role of Irisin, Chemerin and Some Other Hormonal Levels in Obese, Diabetic (type II) and Sub-Fertile Men

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Biochemistry

Abstract

Role of two polypeptides hormones Irisin and chemerin and other hormones (follicular stimulating hormone FSH, luteinizing hormone LH, testosterone T and prolactin PRL) in obese, diabetic and sub-fertile men was investigated. This investigation

has 80 men aged 35-45 years, they were divided into four groups (20 men / group) as control, obesity, diabetic and sub-fertility groups. The results revealed that irisin increased significantly (p ≥ 0.01) in obesity group and decreased significantly in diabetic and sub-fertility groups in compression with the control.

Chemerin increased significantly in different groups in compression with the control (p ≥ 0.01), while FSH, LH and T decreased significantly (except T in diabetic group) in different groups in comparison with the control (p ≥ 0.01). PRL increased significantly in different groups in comparison with the control (p ≥ 0.01). The physiological impact of these results were be discussed according to the influence of the fat mass (indicated by body mass index BMI), insulin resistance (IR) and the high level of prolactin hormone on all the studied parameters in obesity, diabetic and sub-fertility groups.

In conclusion, the irisin and chemerin levels and their relations with the others hormones indicated a metabolic dysfunction and / or a low fertility in these different groups.

DOI

10.21608/ejchem.2022.135007.5939

Keywords

Irisin, Chemerin, Obesity, diabetic, Sub-fertility

Authors

First Name

Raya Najim

Last Name

Rasool

MiddleName

-

Affiliation

Department of Biology, College of Science, University of Misan, Maysan, Iraq

Email

rayaaltimimy@gmail.com

City

-

Orcid

-

First Name

Ahmed Aboud

Last Name

Khalifa

MiddleName

-

Affiliation

Department of Biology, College of Science, University of Misan, Maysan, Iraq

Email

physiologist60@yahoo.com

City

-

Orcid

-

Volume

66

Article Issue

2

Related Issue

39241

Issue Date

2023-02-01

Receive Date

2022-04-20

Publish Date

2023-02-01

Page Start

183

Page End

190

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_241689.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=241689

Order

241,689

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Studying the Role of Irisin, Chemerin and Some Other Hormonal Levels in Obese, Diabetic (type II) and Sub-Fertile Men

Details

Type

Article

Created At

30 Dec 2024