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269664

Spectrophotometric Determination of Mesalazine via Diazotization-Coupling Reaction by Using Thymol Reagent

Article

Last updated: 01 Jan 2025

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Abstract

A simple and sensitive spectrophotometric method has been developed to determine Mesalazine in aqueous solution. The method depends on reaction of Mesalazine with thymol reagent to afford a colored analogue that has absorption band at 436 nm with molar absorptivity of 4149.95 L.mol-1.cm-1. The determination rang was 2-70 µg/ml with recovery 102.4 and relative standard of less than 1.5 %. The proposed method is applied for determination of Mesalazine in pharmaceutical preparation.

DOI

10.21608/ejchem.2022.134639.5927

Keywords

Spectrophotometric, Mesalazine, Diazotization- coupling reaction, Thymol

Authors

First Name

Mohammed

Last Name

Al-Enizzi

MiddleName

S.

Affiliation

Dept.of Chemistry, College of Education for girls, Mosul University, Iraq

Email

mohammmed.salim@uomosul.edu.iq

City

Mosul

Orcid

-

First Name

Intisar

Last Name

Shihab Al-Hammoodi

MiddleName

Adil

Affiliation

Department of Chemistry, college of Education for girls, University of Mosul , Mosul, Iraq

Email

entesar@uomosul.edu.iq

City

Mosul

Orcid

-

First Name

Abdussamed

Last Name

Saeed

MiddleName

M.

Affiliation

Branch of Basic Science, College of Agriculture and Forestry, Mosul University, Iraq

Email

abdmas74@uomosul.edu.iq

City

-

Orcid

-

Volume

65

Article Issue

132

Related Issue

39238

Issue Date

2022-12-01

Receive Date

2022-04-18

Publish Date

2022-12-01

Page Start

1,561

Page End

1,566

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 65_Issue 132_Pages 1561-1566.pdf

PDF . 546.1kB

Link

https://ejchem.journals.ekb.eg/article_269664.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=269664

Order

269,664

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Spectrophotometric Determination of Mesalazine via Diazotization-Coupling Reaction by Using Thymol Reagent

Details

Type

Article

Created At

30 Dec 2024