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380665

Comparison of Fagotti’s index and Sugarbaker’s peritoneal cancer index (PCI) in Predicting Resectability in advanced ovarian cancer

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Obstetrics & Gynaecology

Abstract

Background: Peritoneal carcinomatosis is a condition manifests in advanced stages of ovarian cancer. The primary determinants of total debulking are the disease's volume and distribution. The procedure known as diagnostic laparoscopy makes it possible to assess the illness. The purpose of this study is to evaluate the diagnostic accuracy of two laparoscopic scores—the Fagotti's index and Sugarbaker's peritoneal cancer index (PCI)—in order to reduce the number of needless laparotomies and identify patients who should get neoadjuvant treatment. Methods: This prospective cohort study occurred in Obstetrics and Gynecology Department, Zagazig Gyneoncology Unit (ZGOU), Faculty of Medicine, Zagazig University, Egypt on patients with diagnosis of peritoneal carcinomatosis in advanced ovarian cancer. Fagotti's index and Sugarbaker's peritoneal cancer index were assessed in all cases.

Results: PCI score achieved higher area under the curve (AUC) of 0.920 while Fagotti score had an AUC of 0.823. The PCI score cut-off level for the prediction of resectability was (≥ 15 ) which had a sensitivity of 80% and a specificity of 80%, predictive value for positive (PVP) = (66.7%), predictive value for negative (PVN) = (88.9%), and (80%) accuracy.

Conclusion: Both Sugarbaker's (PCI ) and Fagotti 's index are reliable and accurate indices in predicting resectability in advanced ovarian malignancy with Sugarbaker's (PCI ) being more specific.

DOI

10.21608/zumj.2024.319075.3568

Keywords

Fagotti’s index, Sugarbaker’s peritoneal cancer index, Resectability, ADVANCED OVARIAN CANCER

Authors

First Name

Eman

Last Name

El Gindy

MiddleName

Amin

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University

Email

eman_elgindy2013@hotmail.com

City

-

Orcid

-

First Name

Hussein

Last Name

Abdeldayem

MiddleName

Mohamed

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University

Email

abdeldayemh@yahoo.com

City

zagazig

Orcid

-

First Name

Salah

Last Name

Shahin

MiddleName

El Sayed Kamal

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University

Email

salah.elsayed.kamal.shahin@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Elsayad

MiddleName

H.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig university, Egypt

Email

ahmed.elsayad.g@gmail.com

City

-

Orcid

-

Volume

30

Article Issue

9

Related Issue

51783

Issue Date

2024-12-01

Receive Date

2024-09-07

Publish Date

2024-12-01

Page Start

4,594

Page End

4,607

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_380665.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=380665

Order

31

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Comparison of Fagotti’s index and Sugarbaker’s peritoneal cancer index (PCI) in Predicting Resectability in advanced ovarian cancer

Details

Type

Article

Created At

30 Dec 2024