Purpose: The aim of this work was to evaluate the efficacy of combined continued air pumping and descemetotomy in management of severe post- phacoemulsification Descemet membrane detachment (DMD).

Patients and methods: This study is an interventional study that included 7 eyes of 7 patients who presented with post phacoemulsification corneal edema due to Severe DMD.

Results: The age of the patients at the time of surgery ranged from 61 to 73 years (mean age 66.7 ± 4.27 years). Best corrected visual acuity (BCVA) was improved from 0.076 ± 0.04 preoperatively to 0.53 ± 0.18 six months postoperatively. This difference was statistically significant (P value < 0.05). In all cases the Descemet membrane was completely attached all through the postoperative follow up period which ranged from 6 to 9 months (7.4 ± 1 months). The Central Corneal Thickness CCT was significantly reduced from 874.3 ± 101 um preoperatively to 543 ± 38.6 um six months postoperatively. No hypotony or endophthalmitis were reported.

Conclusion: Combined continued air pumping and descemetotomy is an effective surgical technique in management of large post- phacoemulsification DMD.