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Efficacy of Intravenous Ibuprofen versus Intravenous Ketorolac for Postoperative Pain Following Septorhinoplasty

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Anaesthesia & Surgical Intensive Care

Abstract

Background: Septorhinoplasty is a common surgery patients seek for functional or aesthetic purposes. This study aimed to compare the effects of intravenously administered ibuprofen and intravenously administered ketorolac on postoperative pain relief following septorhinoplasty.

Methods: This study is a double-blind randomized trial. Two equal groups of twenty patients each were randomly selected from a total of forty adult patients of both sexes, ASA I and ASA II, ranging in age from 18 to 60, who were scheduled for elective septorhinoplasty under general anesthesia. Group I and group K were given intravenous ibuprofen ( 800 mg) and intravenous ketorolac (30 mg) respectively every 6 hours starting from induction of anesthesia. Both groups received pethidine as rescue analgesia. VAS evaluations and data on opioid use were documented up to 24 hours postoperatively. Both groups were also compared for intraoperative analgesia and medication-related adverse effects.

Results: Ibuprofen group had lower VAS scores than ketorolac group (p <0.05). While the first call for rescue analgesia was comparable in both groups (p = 0.779), the total dosages and frequency of rescue analgesia consumption were significantly reduced in the ibuprofen group (p = 0.036 and 0.048, respectively). Both groups had no difference regarding heartburn (p = 0.235). However, there was more nausea& vomiting, and intraoperative blood loss in ketorolac group (p = 0.038 and 0.007, respectively).

Conclusion: Intravenous ibuprofen, compared to ketorolac, is associated with lower postoperative VAS scores and less opioid consumption when used to alleviate postoperative pain following septorhinoplasty.

DOI

10.21608/zumj.2024.257108.3062

Keywords

Ibuprofen, Ketorolac, Postoperative Pain, Septorhinoplasty, visual analogue scale

Authors

First Name

Sadik

Last Name

Sadik

MiddleName

Abdel Maseeh

Affiliation

Department of anesthesia and ICU , faculty of medicine, Menoufia university, Egypt

Email

sadek.abd@med.menofia.edu.eg

City

Tala menoufia

Orcid

-

First Name

safa

Last Name

Helal

MiddleName

mohamed

Affiliation

Department of anesthesia and ICU , faculty of medicine, Menoufia university, Egypt

Email

safaa.hilal@med.menofia.edu.eg

City

Shebin ElKom

Orcid

-

First Name

Mohammed

Last Name

Salem

MiddleName

Abdel Rahman

Affiliation

Department of anesthesia and ICU , faculty of medicine, Menoufia university, Egypt

Email

mohamed.salim@med.menofia.edu.eg

City

cairo

Orcid

-

First Name

Mohamed

Last Name

Aboelela

MiddleName

Ali

Affiliation

Department of anesthesia and ICU , faculty of medicine, Menoufia university, Egypt

Email

mohammed.aly1993@gmail.com

City

-

Orcid

-

First Name

Amany

Last Name

Abd El-Haleem

MiddleName

Said

Affiliation

Department of anesthesia and ICU , faculty of medicine, Menoufia university, Egypt

Email

amany.saeed.12@med.menofia.edu.eg

City

cairo

Orcid

-

Volume

30

Article Issue

1.7

Related Issue

51083

Issue Date

2024-10-01

Receive Date

2023-12-26

Publish Date

2024-10-01

Page Start

3,847

Page End

3,859

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_334813.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=334813

Order

15

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Efficacy of Intravenous Ibuprofen versus Intravenous Ketorolac for Postoperative Pain Following Septorhinoplasty

Details

Type

Article

Created At

30 Dec 2024