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338691

Cutaneous leishmaniasis: Clinical Picture, Diagnosis and Differential Diagnosis

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Dermatology & Venereology

Abstract

Cutaneous leishmaniasis (CL) is caused by female sandflies carrying the protozoan parasite Leishmania, which is a vector-borne disease. There are 12 million cases overall with an annual incidence of 2–2.5 million. CL is classified by the World Health Organization as a category 1 emerging and uncontrolled disease and as a seriously neglected disease. Because of the significant clinical diversity and overlap across the Leishmania species, none of the clinical manifestations are specific to a single species, despite the fact that each may have its own peculiar signs and areas of endemicity. This is due to the fact that factors pertaining to both the host and the Leishmanian species that induce infection affect the clinical picture. These include the parasite's virulence, infectiousness, hematogenous and lymphatic dissemination, immunological response, and host genetic susceptibility. It used to be quite difficult to identify the infecting parasite, but new DNA techniques have made it reasonably easy to identify the Leishmania species, allowing for a more informed choice of therapy. The recent advancements in the diagnosis of cutaneous leishmaniasis (CL), which is brought on by both Old and New World Leishmania species, are the main topic of this review.

DOI

10.21608/zumj.2024.260932.3095

Keywords

Cutaneous, Leishmaniasis, parasite

Authors

First Name

Amani

Last Name

Mohammed Alasswad

MiddleName

Masoud

Affiliation

(M.B., B. Ch) Faculty of Medicine- Gharyan University – Libya

Email

amanialaswad04@gmail.com

City

-

Orcid

-

First Name

Amany

Last Name

Nassar

MiddleName

-

Affiliation

Dermatology department Zagazig university

Email

dramany_nassar@yahoo.com

City

-

Orcid

-

First Name

Khamees

Last Name

Mohammed

MiddleName

Almabrouk

Affiliation

Assistant Professor, Consultant Dermatologist Medical College, Gharyan University, Gharyan Central Teaching Hospital, Libya

Email

dkhamis62@gmail.com

City

-

Orcid

-

First Name

Hagar

Last Name

Nofal

MiddleName

-

Affiliation

Department of Dermatology and venerology, Faculty of medicine, Zagazig University, Zagazig, Egypt

Email

hagarnofal2@gmail.com

City

-

Orcid

-

Volume

30

Article Issue

1.7

Related Issue

51083

Issue Date

2024-10-01

Receive Date

2024-01-06

Publish Date

2024-10-01

Page Start

3,743

Page End

3,753

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_338691.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=338691

Order

6

Type

Review Articles

Type Code

349

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Cutaneous leishmaniasis: Clinical Picture, Diagnosis and Differential Diagnosis

Details

Type

Article

Created At

30 Dec 2024