Background: Cesarean section in second stage with full cervical dilation is linked to an increased risk of maternal and fetal problems because of the thinned-out, edematous lower segment and the highly impacted fetal head in the pelvis, which make the procedure technically challenging. The current study aimed to evaluate the maternal and neonatal complications of caesarean section in second stage of labour. Patients and methods: Prospective Observational study conducted in Maternity Hospital at Zagazig University. Included 24 patients with a singleton fetus in cephalic presentation and pregnancy ≥ 37 weeks gestation who underwent emergency CS in second stage of labour. All women were subjected to complete history taking, General examination and Laboratory investigation. Results: This study results showed that most common intraoperative complications were bladder injury, uterine artery ligation and hemorrhage. The most common postoperative maternal complications were wound infection and Postpartum hemorrhage (PPH) while fetal complications were meconium aspiration, Apgar score ≤ 7 and respiratory distress. There was no statistically significant difference between maternal complicated cases and non-complicated cases regarding demographic data or history or labour data. Moreover, there was no statistically significant difference between fetal complicated and non-complicated cases in demographic data or history or labour data. Conclusion: we concluded that CS in the second stage of labour showed higher risk of maternal complications either intraoperative or postoperative, in addition risk of fetal complications also rise with CS in the second stage of labour.