Background: Every year, millions of people are affected with sepsis and septic shock, which pose significant challenges to healthcare providers. Septic shock is the most severe form of sepsis.

Aim & objectives: To assess rate of Admission & Risk factors in sepsis and septic shock patients in Emergency Intensive Care Unit (EICU) at Zagazig University Hospitals. And to compare between sepsis and septic shock patients regarding frequency and risk factors in EICU.

Patients and methods: This prospective cohort research was done on 360 cases that were collected in 6-months period, aged 18 years old or more both sexes sepsis & septic shock cases in EICU at Zagazig University Hospitals. Our cases were separated into three groups in accordance with the cause of admission; Group A involved 284 cases with non-sepsis non-septic shock indications, Group B involved 40 cases with sepsis, and Group C involved 36 cases with septic shock.

Results: There was a significantly variance among the studied groups concerning age, gender, BMI, vital signs, laboratory parameters, kidney function, systemic inflammatory markers (CRP), serum PCT, serum electrolytes, sodium levels, serum potassium and liver function tests (serum bilirubin and hepatic transaminases). While there was no significantly difference regarding prevalence of medical comorbidities

The indication for ICU admission included sepsis (11.1%) and septic shock (10%), while the remaining patients had non-sepsis non-septic shock indications.

Conclusion: Incidents of sepsis and septic shock, which can lead to increased mortality and morbidity, continue to be prevalent in ICUs in LMIC.