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317405

OCT biomarkers in predicting postoperative visual acuity after primary vitrectomy for rhegmatogenous retinal detachment

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Ophthalmology

Abstract

Background: Optical coherent tomography (OCT) is a noninvasive technique that has the advantage of imaging and quantitatively analyzing retinal thickness, nerve fiber layer, and optic nerve structures with good reproducibility. With OCT, several studies reported that retinal microstructures are important to the visual prognosis after macula off RRD surgery. According to these studies, integrity of the ellipsoid zone (EZ) and external limiting membrane (ELM) and presence of foveal bulge are significantly correlated with postoperative best corrected visual acuity (BCVA). This study aims to find postoperative factors related to changes of visual acuity after macular-off RRD surgery by analyzing OCT findings.



Methods: 74 patients who were planned to undergo pars plana vitrectomy to repair macula-off rhegmatogenous retinal detachment. After surgical clinical success, patients were divided according to postoperative BCVA at the 6th month after surgery into two groups: Group A (Poor visual acuity <6/60) and Group B (Good visual acuity ≥ 6/60).

Results: At the 1st month after the surgery, BCVA, central macular thickness (CMT), residual subretinal fluid (SRF) and ELM and EZ integrity was significantly associated with the final visual acuity (p=0.002, 0.033, 0.007 and 0.013). At the 3rd month, BCVA, ELM and EZ integrity were associated with the final visual acuity (p=<0.001, 0.011 and 0.001 respectively). At the 6th month, ELM and EZ integrity was associated with the final visual acuity (p=0.002 and <0.001 respectively)

Conclusion: ELM and EZ integrity significantly influenced the final visual acuity at the 6th month after the surgery.

DOI

10.21608/zumj.2023.236131.2888

Keywords

rhegmatogenous detachment, BCVA, Pars Plana Vitrectomy, ELM, EZ

Authors

First Name

Mahmud

Last Name

Mahmud Nasif

MiddleName

Mohammed Magdy

Affiliation

Ophthalmology department, Faculty of medicine, Zagazig University, Zagazig, Sharkia, Egypt

Email

mhmud.mgdy@gmail.com

City

-

Orcid

0000-0003-4558-5359

First Name

Mohamed

Last Name

Awad

MiddleName

Bahgat Elsayed

Affiliation

Ophthalmology Department, Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt

Email

m_b_awad@hotmail.com

City

Zagazig

Orcid

-

First Name

Hassan

Last Name

Hanifa

MiddleName

Ali Zaki

Affiliation

Ophthalmology department, Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt

Email

dr.hassanhanifa@yahoo.com

City

Damietta

Orcid

-

First Name

Alaa

Last Name

Hamdy

MiddleName

Mohammed

Affiliation

Opthalmology department, Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt

Email

hamdi_alaa@yahoo.com

City

zagazig

Orcid

-

Volume

30

Article Issue

1.6

Related Issue

50336

Issue Date

2024-09-01

Receive Date

2023-09-12

Publish Date

2024-09-01

Page Start

3,020

Page End

3,032

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_317405.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=317405

Order

34

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

OCT biomarkers in predicting postoperative visual acuity after primary vitrectomy for rhegmatogenous retinal detachment

Details

Type

Article

Created At

30 Dec 2024