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Sentinel Lymph Node Biopsy in Early Breast Cancer Using Patent Blue Dye as a Single Identification Method: Experience of an Academic Center

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

General Surgery

Abstract

Introduction Sentinel lymph node biopsy (SLNB) has become the standard of care in the assessment of metastatic spread to axillary lymph nodes in cases with early breast cancer. The use of single or dual method for identification of the sentinel nodes was an area of much research that concluded that dual method using both dye and radiolabeled tracer has a preference given higher identification rates. Methods In this study we assessed our experience with SLNB using patent blue dye in the period 2019-2023 in patients with early breast cancer eligible for SLNB treated in Suez Canal University Hospitals. The primary outcome was to estimate the identification rate and percentage of upstaging and need for axillary dissection (AD) following SLNB. Results A total of 128 patients were included and successful identification of SLN was attained in 122 patients (95.3%). 95 of them showed negative nodes while metastatic deposits was identified in 27 patients ( 22.1%) that necessitated completion axillary clearance in 16 ( 13.1%). Conclusion SLNB is a reliable method even in the setting allowing only single method of identification giving patients with early breast cancer the chance to avoid unnecessary axillary clearance and its future morbidity.

DOI

10.21608/zumj.2024.269494.3167

Keywords

sentinel lymph node biopsy, breast cancer, Dye method, Identification rate, Axillary nodes

Authors

First Name

Ahmed

Last Name

Gomaa

MiddleName

-

Affiliation

Surgical Oncology, Faculty of Medicine, Suez Canal University

Email

gomaaahmed@hotmail.com

City

-

Orcid

-

First Name

Mahmoud

Last Name

Hussin

MiddleName

Gamal Moustafa

Affiliation

Surgical Oncology, Faculty of Medicine Suez Canal University

Email

mgmhussin@gmail.com

City

-

Orcid

-

First Name

Ayman

Last Name

Gomaa

MiddleName

Mohamed Mahmoud

Affiliation

Surgical Oncology Faculty of Medicine Suez Canal University

Email

aymenmgo@hotmail.com

City

-

Orcid

-

Volume

30

Article Issue

5

Related Issue

49235

Issue Date

2024-08-01

Receive Date

2024-02-11

Publish Date

2024-08-01

Page Start

1,531

Page End

1,541

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_343210.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=343210

Order

343,210

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Sentinel Lymph Node Biopsy in Early Breast Cancer Using Patent Blue Dye as a Single Identification Method: Experience of an Academic Center

Details

Type

Article

Created At

30 Dec 2024