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198083

Efficacy of perioperative levosimendan on cardiac protection in patients undergoing coronary artery bypass surgery

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Cardiothoracic Surgery

Abstract

These risks have led to the appearance of several ways to provide better outcomes. These ways are either mechanical like intraaortic balloon pump (IABP) or using medical inotropic drugs either adrenergic (epinephrine, norepinephrine &dobutamine) or non-adrenergic (levosimendan) drugs. It is indicated for the short-term treatment of acutely
Patients and Method
Patients had collected, withpoor left ventricular function ejection less than or equal to 40%. Cases had allocated into two gatherings of 50 cases.cases had admitted to the cardiovascular intensive care unit (ICU) 24h before surgery, a peri-operative dose of continuous levosimendan infusion cases will be submitted to conventional inotropes only (non levosimendan gathering) according to their medical requirements.

Objective: to detect the outcome of clinical use of preioperative Levosemindan for cases undergoing coronary artery bypass grafting comparing it with the conventional medications as catecholamines.
Results
Gathering A included 38 cases received levosimendan Gathering B included 40 cases received conventional cardiac support. A critical difference between both gatherings regarding total operative time, total bypass time, failure of weaning from cardiobypass (C.P.B), the use of intraoperative I.A.B.P.. There had a statistically critical difference between both gatherings in which C.V.P had lower in levosimendan .There had statistically critical difference regarding base critical in the levosimendan gathering. with high statistical difference for medical support, no difference for support .
Conclusion
the use of levosimendan perioperative is useful than cathecholamins

DOI

10.21608/zumj.2021.97258.2353

Keywords

poor, left ventricular, CABG, levosemindan

Authors

First Name

mahmoud

Last Name

abdrabo

MiddleName

mohamed

Affiliation

cardiothoracic surgery department ,faculty of medecine zagazig university

Email

mahmoudabdrabo@gmail.com

City

cairo

Orcid

-

First Name

mohamed

Last Name

Elsharawy

MiddleName

mamdouh

Affiliation

cardiothoracic department,faculty of medecine Zgazig university,

Email

mamdouhelsharawy@yahoo.com

City

Zagazig

Orcid

-

First Name

Adel

Last Name

ragheb

MiddleName

Ragheb

Affiliation

cardiothoraci surgery department ,natoinal heart institute

Email

adelragheb@gmail.com

City

cairo

Orcid

-

First Name

dina

Last Name

osman

MiddleName

mohamed

Affiliation

cardiothoracic surgery zagazig university egypt

Email

elfekydina03@gmail.com

City

zagazig

Orcid

-

Volume

30

Article Issue

1.4

Related Issue

48036

Issue Date

2024-06-01

Receive Date

2021-09-21

Publish Date

2024-06-01

Page Start

235

Page End

246

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_198083.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=198083

Order

21

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Efficacy of perioperative levosimendan on cardiac protection in patients undergoing coronary artery bypass surgery

Details

Type

Article

Created At

30 Dec 2024