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Effect of Preoperative Level of Hemoglobin A1C on Early Outcome After Coronary Artery Bypass Graft Surgery

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Cardiothoracic Surgery

Abstract

Objective: Diabetics represent an increasing proportion of patients undergoing coronary artery bypass graft (CABG). Glycosylated hemoglobin (HbA1C) is a key indicator for glycemic control. The degree of glycemic control is directly reflected in the outcome after CABG. Our study aims to analyze the early outcome concerning preoperative HbA1C levels. Methods: This prospective study evaluated the early outcome of 623 isolated elective CABG patients over 19 months. The patients were divided into group A (347 patients) with HbA1C < 7% and group B (276 patients) with HbA1C ≥ 7%. Postoperative renal failure, myocardial infarction, atrial fibrillation (AF), wound infection, cerebrovascular accidents, and 30-day mortality were recorded. Results: Baseline characteristics showed a non-significant difference between both groups. The mean age of patients in group A was 59.6 years, and in group B it was 59.5 years. The mean graft number was 3.35 and 3.32 for groups A and B, respectively. First-month death was 0.9% in group A and 1.4% in group B without a significant difference. The incidence of AF, superficial wound infection, and other site infections showed a statistically substantial difference between both groups. Conclusion: Increased levels of HbA1c, more than 7%, may be a potential risk factor for postoperative complications with a substantial rise in the risk of wound infections (superficial sternal and non-sternal surgical) and AF.

DOI

10.21608/zumj.2022.157231.2624

Keywords

Keywords: Glycosylated hemoglobin, HbA1c, CABG, Sternal Wound Infection

Authors

First Name

Ashraf

Last Name

Abdelsalam

MiddleName

Hamed

Affiliation

Cardiothoracic surgery department, Faculty of Medicine, Zagazig University

Email

ashrafhamid73@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Deebis

MiddleName

Mohammed

Affiliation

Cardiothoracic Surgery Department, Faculty of Medicine, Zagazig University, Egypt

Email

ahmeddeebis@gmail.com

City

-

Orcid

0000-0002-3519-172x

First Name

Amr

Last Name

Mansour

MiddleName

Hassan

Affiliation

Department of Cardiothoracic surgery, Zagazig University, Egypt

Email

amrh_man78@yahoo.com

City

Zagazig

Orcid

-

First Name

Alawab

Last Name

Mesallam

MiddleName

Mohammed

Affiliation

Cardiothoracic Surgery Department, Alahrar Educational Hospital, Zagazig, Egypt

Email

dr_awab_cts2006@yahoo.com

City

-

Orcid

-

First Name

Tamer

Last Name

Goda

MiddleName

Mohamed

Affiliation

Intenal nedicine department,, zagazig university

Email

drtamer107@gmail.com

City

-

Orcid

-

First Name

Niveen

Last Name

Shafeek Shokry Sakla

MiddleName

-

Affiliation

Nephrology Unit-Zagazig University

Email

drniveen.shafeek@yahoo.com

City

-

Orcid

-

First Name

Tamer

Last Name

Alawady

MiddleName

Salem

Affiliation

cardiothoracic surgery department, faculty medicine, zagazig university, zagazig, egypt

Email

talawady73@yahoo.com

City

zagazig

Orcid

-

Volume

30

Article Issue

1.3

Related Issue

47218

Issue Date

2024-04-01

Receive Date

2022-08-19

Publish Date

2024-04-01

Page Start

155

Page End

161

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_257717.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=257717

Order

19

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Effect of Preoperative Level of Hemoglobin A1C on Early Outcome After Coronary Artery Bypass Graft Surgery

Details

Type

Article

Created At

30 Dec 2024