Abstract

Background: Cardiovascular disease is the leading cause of death in chronic kidney disease children (CKD). Due to their susceptibility to accelerated atherosclerosis, these children are classified as having the greatest level of cardiovascular risk in the American Heart Association's pediatric consensus guidelines for cardiovascular health. Our study intended to improve the early diagnosis of atherosclerosis in children with End-Stage Renal Disease (ESRD).
Methodology: a case-control study involved two groups, ESRD group was 20 cases, males represented 60%, and females represented 40%, the median age was 13 years ranging from 6-18 years, they were on regular hemodialysis, which was done three times per week for four h with standard bicarbonate dialysis. Hemodialysis was carried through an upper limb arteriovenous fistula by Fresenius medical care 4008 S machine made in Germany. Control: apparently, healthy 25 children of matched age and sex came from outpatient for minor diseases and patient relatives.
Results: There was a statistically significant reduction in BMI in patients with ESRD compared to control. ESRD patients also had higher systolic and diastolic blood pressure, urea, creatine, CRP, TGS, and PTH than control subjects.
Conclusion: The most prevalent Dyslipidemia in ESRD was hypertriglyceridemia, low HDL, increased LDL, and total cholesterol.
Keywords: Chronic Kidney Disease, Atherosclerosis, End-Stage Renal Disease & ESRD.