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206727

Assessment risk factors and different lines of treatment of anemia in kidney transplant recipients

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Internal Medicine

Abstract

Aim
Screening of the prevalence, etiologies of post transplantation anemia PTA, its implication on graft function and efficacy of different approaches in the management of anemia in a cohort of kidney transplant recipients .

Patient and methods:
We studied 320 kidney transplant recipients; 160 cases (anemic patients ) and 160 control (normal Hb group < br>Univariate and multivariate analysis were done to evaluate the risk of anemia .A prospective investigation of various etiologies of anemia post renal transplantation were done. complete blood picture, Iron indices ,kidney function.
management of anemia according to condition was administered either by Iron therapy or erythropoietin stimulating agents (ESA) therapy Re-evaluation was done after 3 months of. Resistant cases managed by bone marrow biopsy or modify immunosuppression.

Results:
Our cohort included 320 patients with multiple risk factors that showed statistical significance by Univariate analysis.
Incidence of anemia in our group was 25 % per year and prevalence was 20 %.
The risk factors of PTA in our study were female gender, old donors (, low pre transplant Hemoglobin , of acute rejection, chronic rejection , , Bacterial infections.
Low iron indices were also risk factors; and associated with Low eGFR in anemic patients .
Conclusion:
The risk factors of PTA in our study were female gender , old donors, low pre transplant Hemoglobin, acute and chronic rejection , number of acute rejections, bacterial infections and low iron indices associated with progressive decline eGFR.

DOI

10.21608/zumj.2021.102480.2393

Keywords

Anemia, kidney transplant, Post transplantation anemia

Authors

First Name

Mohamed

Last Name

Elsaftawy

MiddleName

Mohamed

Affiliation

urology&amp;amp; Neperology center Mansoura University

Email

drmoh_saft@yahoo.com

City

-

Orcid

-

First Name

Medhat

Last Name

Mahmoud

MiddleName

Ibrahim

Affiliation

Internal Medicine, Faculty of medicine, zagazig University

Email

ibrahim_medhat_73@yahoo.com

City

Zagazig

Orcid

-

First Name

Yaser

Last Name

Elhendy

MiddleName

Abdelmoniem

Affiliation

Internal medicine, faculty of medicine zagazig University zagazig Egypt

Email

yaserhendy@gmail.com

City

Zagazig

Orcid

-

First Name

Ahmed

Last Name

Akl

MiddleName

Ibrahim

Affiliation

Consultant Of Nephrology, Urology And Nephrology Center; Mansoura University

Email

aiakl2001@yahoo.com

City

Mansourra

Orcid

-

Volume

30

Article Issue

1.2

Related Issue

45958

Issue Date

2024-02-01

Receive Date

2021-10-31

Publish Date

2024-02-01

Page Start

61

Page End

71

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_206727.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=206727

Order

8

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Assessment risk factors and different lines of treatment of anemia in kidney transplant recipients

Details

Type

Article

Created At

30 Dec 2024