Beta
183128

Outcome of Immediate versus Delayed Stenting in ST-segment Elevation Myocardial Infarction Patients with High Thrombus Burden

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Cardiology

Abstract

The safety of deferred stenting as a technique in STEMI patients is questioned by guidelines. Objectives: To see how effective immediate stenting versus delayed stenting is at lowering angiographic outcomes (no/slow reflow, distal embolization, and improved myocardial blush grade MBG) in STEMI patients. One of the clinical outcome criteria utilized to assess the study (during the initial stay and 6 months after discharge) was the incidence of Major adverse cardiac events(MACE). Methods: 108 patients of STEMI with heavy thrombus burden divided equally into 2 groups: Group (1): 54 patients treated with immediate stenting and Group (2) 54 patients treated with deferred stenting. Procedural angiographic events were the primary endpoints, while in MACE and bleeding complication were the secondary endpoints. Results: Deferred stenting patients had a statistically significant decrease in slow flow and no reflow (P = 0.03). defer group showed a greater increase in myocardial blush grade (MBG) than immediate stenting group. (p value 0.04). Distal embolization showed no statistical difference (p value 0.1), and there was no significant variation between the two classes in terms of bleeding complications (p value 0.7). Also, there was no statistically improvement in the deferred stenting group (P value = 0.3) by comparing the Composite of MACEs between the two classes. Conclusion Deferred stenting was associated with improved immediate myocardial perfusion, less no/slow reflow, and distal embolization, but not with a decrease in MACEs at 6 months, so direct stenting is a standard treatment option for STEMI patients

DOI

10.21608/zumj.2021.78875.2251

Keywords

No reflow, Microvascular obstruction, STEMI, Delayed stenting

Authors

First Name

Kamel

Last Name

Mohamed ghazal

MiddleName

Hassan

Affiliation

Cardiology departement , faculty of medicine, zagazig university

Email

kamelghazal535@yahoo.com

City

-

Orcid

-

First Name

Ekhlas

Last Name

Hussein

MiddleName

M.

Affiliation

cardiology department-zagazig university

Email

card_20002000@yahoo.com

City

-

Orcid

https://orcid.org/00

First Name

Mohammad

Last Name

Mohammad

MiddleName

Gouda

Affiliation

Cardiology department, Faculty of medicine, Zagazig university, Zagazig, Egypt

Email

-

City

zagazig

Orcid

-

First Name

Wesam

Last Name

Hozien

MiddleName

Rabieh

Affiliation

department of cariology - National heart institute -Giza work as aphysician

Email

weasm.hozien@hotmail.com

City

abu hammad -sharkia

Orcid

-

Volume

30

Article Issue

2

Related Issue

45687

Issue Date

2024-03-01

Receive Date

2021-06-14

Publish Date

2024-03-01

Page Start

350

Page End

357

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_183128.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=183128

Order

6

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Outcome of Immediate versus Delayed Stenting in ST-segment Elevation Myocardial Infarction Patients with High Thrombus Burden

Details

Type

Article

Created At

30 Dec 2024