Background: Most of cardiovascular (CV) events in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) are linked to the progression of non-culprit coronary lesions (NCCLs) during the follow-up period. Yet, the clinical and angiographic risk factors of non-culprit coronary lesion (NCCL) progression are not well known.
Objectives: To assess the clinical risk profile and angiographic features that can be related to the progression of non-culprit lesions (NCLs) of patients with STEMI undergoing PCI over 24 months duration.
Subjects and methods: The present cohort study evaluated 200 patients with STEMI underwent PCI to the culprit lesion and have mild non culprit lesion (NCL) 1.4mmol/L) (OR:54.656, 95% CI: 4.052 to 737.256; p= 0.003), Complex culprit lesion(OR:296.112, 95% CI: 13.673 to 6412.728; p < 0.001), and presence of more than one NCL (OR:22.447, 95% CI: 2.521 to 199.849; p= 0.005).
Conclusion: The underlying clinical and angiographic characteristics can predict NCLs progression. Complex morphology of culprit lesion is the strongest independent predictor for progression of NCLs.