Background: Appendicitis is most found in the second decade of life. It can be categorised into two major categories: uncomplicated and complicated appendicitis. Laparoscopic appendectomy (LA) and Open appendectomy (OA) are two common techniques for the surgical removal of appendices in acute appendicitis. The goal of this research was to examine and explain the effectiveness of laparoscopic appendectomy in patients with complicated appendicitis. Patients and methods: A retrospective study was carried out in General Surgery Department, Faculty of Medicine, Zagazig University from March 2020 to September 2020. It involved 36 patients with reported complicated appendicitis randomly assigned (through alternation) to two groups of 18 patients, Group A; patients underwent open appendectomy by gridiron incision at McBurney stage. Group B; patients undergoing laparoscopic appendectomy. All patients were subjected to demographic data taking, complete clinical examination, Laboratory investigations and Radiological investigation. Results: Postoperative wound infection was higher in the open group (A) than in the laparoscopic group (B), but did not display a substantial difference (33.3 per cent infected in open cases and just 11.1 per cent infected in laparoscopic cases) with PV=0.23. Postoperative hospital stays and the time required to return to usual everyday practises were lower in laparoscopic group (B) than in open group (A with P Value = 0.09 and 0.0002 respectively. Conclusion: LA constitutes a safe and feasible procedure for the treatment of complicated appendicitis and can be the first choice with no increase in postoperative complications.