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295279

Effectiveness and Pregnancy Outcomes of COVID-19 Vaccination in Pregnancy

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Obstetrics & Gynaecology

Abstract

Background: Vaccination against COVID-19 during pregnancy is suggested to avoid pregnancy complications morbidity and bad delivery outcomes. However, the safety and efficacy of COVID-19 vaccinations during pregnancy is a specific issue impacting vaccination uptake by this susceptible group due to alterations in immune, respiratory, and cardiovascular physiology that occur during pregnancy. The purpose of this study was to examine the relationship between prenatal mother COVID-19 immunization, pregnancy course, and outcomes. Patients and Methods: A retroactive cohort analysis was conducted on all women who gave birth. Women having a previous COVID-19 diagnosis, numerous pregnancies, or an uncertain vaccination status were excluded. Pregnancy, neonatal problems, and delivery were compared with women who got 1 or 2 doses of a vaccine throughout pregnancy and women who did not get any vaccinations. Using multivariable models, the background characteristics were accounted for. Results: The pregnancy complications were higher in unvaccinated group than vaccinated group with no statistical significant difference except stillbirth that was present only in unvaccinated group (3%). Women who were vaccinated gave birth at a significantly later gestational age. No differences between the groups were detected in terms of postpartum and delivery factors. Women who received vaccination delivered at slightly higher birth weight. No differences were detected in terms of neonatal features and problems between the two groups. Conclusions: We concluded that COVID-19-vaccinated pregnant women experienced similar pregnancy outcomes as unvaccinated pregnant women. In some cases, vaccination proved to be better outcome than un-vaccination.

DOI

10.21608/zumj.2023.199104.2766

Keywords

COVID-19, Pregnancy, Vaccination, Prenatal, outcomes

Authors

First Name

Ahmed

Last Name

Ismail Heraiz

MiddleName

-

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University

Email

ahmedismail_obg@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Zaitoun

MiddleName

Moustafa

Affiliation

Lecturer of Obstetrics & Gynecology , Department, Faculty of Medicine, Zagazig University, Zagazig

Email

zaitounmm@gmail.com

City

-

Orcid

0000-0002-3457-143X

First Name

Abdalla

Last Name

Gad

MiddleName

Hassan

Affiliation

Lecturer of obstetrics and gynecology, Faculty of Medicine, Zagazig University hospitals

Email

dr.abhassang@gmail.com

City

-

Orcid

-

First Name

Noha

Last Name

Frere

MiddleName

Osman

Affiliation

Lecturer of Family Medicine Department, Zagazig University , Zagazig, Egypt

Email

nofrere@medicine.zu.edu.eg

City

-

Orcid

0000-0001-6078-8790

First Name

Nahla

Last Name

Zaitoun

MiddleName

A.

Affiliation

Family Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Email

nahla_zaitoun@hotmail.com

City

-

Orcid

0000-0002-5274-6061

First Name

Al Zahraa

Last Name

Soliman

MiddleName

M.

Affiliation

Lecturer of Public health and community medicine, faculty of medicine, Zagazig University

Email

emsolyman@medicine.zu.edu.eg

City

-

Orcid

0000-0002-3722-6017

First Name

Alaa

Last Name

Nafea

MiddleName

-

Affiliation

Pediatrics Department, Faculty of Medicine, Zagazig University

Email

alaasnafea@gmail.com

City

zagazig

Orcid

-

First Name

AMR

Last Name

Risha

MiddleName

I.

Affiliation

Pediatrics Department, Faculty of Medicine, Zagazig University

Email

dr.amribrahim@ymail.com

City

zagazig

Orcid

-

First Name

Eslam

Last Name

Elshafey

MiddleName

-

Affiliation

Clinical Pathology Department, Al-Ahrar Zagazig Teaching Hospital

Email

eslamelshafey245@gmail.com

City

-

Orcid

-

Volume

29

Article Issue

4

Related Issue

42216

Issue Date

2023-07-01

Receive Date

2023-03-09

Publish Date

2023-07-01

Page Start

1,092

Page End

1,098

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_295279.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=295279

Order

15

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Effectiveness and Pregnancy Outcomes of COVID-19 Vaccination in Pregnancy

Details

Type

Article

Created At

30 Dec 2024