Abstract: Background: Hydatid disease caused by zoonosis. Many ways for treatment have been described depending on cyst number, site, surgeon expertise, and complicated or not. Liver is the most common organ to be affected by Echinococcus. We discuss our results regarding radical surgical management of hepatic hydatid cysts. Methods: a retrospective study regarding radical surgical management of hepatic hydatid cysts at Zagazig University Hospitals, General Surgery Department. From June 2011 to October 2021 on 125 patients presented with hepatic hydatid cyst. Results: Total peri-cystectomy was done in 100 (80%) patients, while liver resection was in 19 (15.2%) patients, laparoscopic procedure used in 6 (4.8%) patients (5 patients with total peri-cystectomy and only one patient needs omento-plasty with sub-total peri-cystectomy). 34 patients developed post-operative complications; 19 patients suffered from biliary leak. We had no mortality. Follow-up period ranged from 6 to 60 months with no recurrence. Conclusion: Hepato-Biliary experienced surgeons favoured for best results in management of hepatic hydatid cysts. Radical surgical procedures carry an efficient and safe results in dealing with hepatic hydatid cysts, with promising data regarding morbidity and recurrence rates.