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Intralesional Injection of Bleomycin In The Treatment of Keloids

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Dermatology & Venereology

Abstract

Background: Keloid is a common clinical distressing problem. Its treatment is a challenging process due to its high rate of recurrence and resistance to some therapies. The aim of this study is to evaluate the efficacy and safety of intralesional injection of bleomycin in the treatment of keloids.
Subject and Methods: Ten patients with keloid lesions were included in this study. Patients were injected every 2 weeks for 6 sessions using intralesional injection of bleomycin at a concentration of 1.5 IU/ml in normal saline solution with a maximum dose of 6 ml per session.
Results: The results were satisfying as percentage of improvement after treatment was 60% according to Vancouver score and was (80% & 87.5%) according to pain and pruritus scores respectively.
Conclusion: Intralesional injection of bleomycin is an effective and safe modality in the treatment of keloids.
Key words: Keloid, Intralesional, Bleomycin.
Corresponding Author: Wesam Khaled Mohamed Emam,
Wesamkhaled88@Gmail.com,01111328143.

DOI

10.21608/zumj.2020.23738.1733

Keywords

Keloid, Intralesional, Bleomycin

Authors

First Name

Amr

Last Name

Saadawi

MiddleName

Nazir

Affiliation

Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Email

amrsaadawi@yahoo.com

City

-

Orcid

-

First Name

Shrook

Last Name

Khashaba

MiddleName

Abd Elshafy

Affiliation

Dermatology, Venereology and Andrology Department, faculty of Medicine, Zagazig University,Zagazig, Egypt

Email

shrook_khashaba@yahoo.com

City

-

Orcid

0000-0003-2593-6908

First Name

Wesam

Last Name

Emam

MiddleName

khaled

Affiliation

Dermatology, Venereology and Andrology department, Belbeis central hospital, Al-sharkia, Egypt.

Email

wesamkhaled88@gmail.com

City

-

Orcid

-

Volume

29

Article Issue

1.2

Related Issue

39915

Issue Date

2023-01-01

Receive Date

2020-02-12

Publish Date

2023-01-01

Page Start

25

Page End

30

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_127818.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=127818

Order

588

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Intralesional Injection of Bleomycin In The Treatment of Keloids

Details

Type

Article

Created At

30 Dec 2024