Abstract Background: Third ventricular colloid cysts are rare be-nign lesion that can usually cause obstructive hydrocephalus, increased intracranial pressure and sometimes death. Surgery for these lesions was usually performed through a craniotomy using the surgical microscope. With the introduction of the neu-roendoscopy, surgical resection has been shifting to the use of the endoscope. Aim of Study: This study aimed at studying the feasibility and complications of endoscopic resection of third ventricular colloid cysts. Patients and Methods: Between 2013 and 2019, all pa-tients (13) who received surgical endoscopic removal of col-loid cysts of the third ventricle at Cairo University Hospital in Cairo, Egypt, were included in the study. Patient charts were assessed for information on pre-and postoperative symptoms, as well as complications. MRI or CT scans were used to meas-ure the maximum cyst diameter and Evans' index. The average period of follow-up was 34 months. Three patients were lost to follow-up. Results: The average patient age was 34 years old (±8.5) at time of surgery. We have got 5 females and 8 males. Mean postoperative hospital stay was 13.5 days (±SD 11.3). Table (1) depicts the present symptoms, surgical improvement, and com-plications. Six patients (46%) presented with hydrocephalus symptoms. When the colloid cyst was removed, an EVD was implanted to monitor intracranial pressure for a maximum of two days after surgery. Postoperative complications happened in 3 cases (23%) of the cases. Conclusion: This surgical method employs burr holes rath-er than craniotomies, with no retraction of the brain, needs a shorter operational time, a shorter hospital stays, and results in greater of satisfaction levels for the patient. Furthermore, the endoscopic technique is safer and more effective, with reduced rates of recurrence and complications.