Abstract Background: Nearly everyone will at some point in their lifetime have low back pain, which is a relatively common ail-ment. A condition referred to as “nonspecific low back pain" lacks a recognized underlying anatomical etiology. According to several publications, it has been widely reported that core stability exercises, particularly those focusing on the transverse abdominis and multifidus muscles, have the potential to reduce chronic low back pain, both with and without radiculopathy, while also enhancing general functionality. Aim of Study: To examine the effect of core stability exer-ciseson chronic non-specific low back pain sufferers. Subjects and Methods: Fifty women with non-specific low back pain were recruited, and participants were divided into two equal groups at random. Study group (A) 25 patients who received core stability exercises and transcutaneous electrical nerve stimulation (TENS). Control group (B) 25 patients who received TENS only. The treatment was conducted for 40min, three sessions per week for twelve successive weeks. Outcome measures were Visual Analogue Scale (VAS) score to measure pain. The measurements were done before and after the 4 weeks of intervention. Results: Within groups comparisons, there was a statisti-cally significant reduction in pain when comparing pre- and post-treatment conditions within study group A, (p=0.001*). While the control group (B), showed a statistically significant reduction in pain when comparing pre- and post-treatment con-ditions (p=0.001*). Between groups comparisons showed a statistical significant reduction in pain for the study group com-pared to the control group after treatment (p=0.001*). Conclusion: Core stability exercises is a beneficial ther-apeutic program in reducing pain in patients with chronic non-specific low back pain.