Abstract Background: Chronic pelvic pain syndrome (CPPS) or National Institutes of Health (NIT) type IIIA/IIIB prostatitis is characterized by pelvic pain and voiding symptoms. The source of the symptoms is still poorly understood, but pain associated with chronic tension and spasm of the pelvic floor muscles (pelvic floor tension myalgia) has been hypothesized to be a contributing factor. Aim of Study: To evaluate the therapeutic efficacy of the perineal high voltage tiny impulses electrical stimulation of pain gone pen (PGP) in decreasing pain and improving the pelvic floor tension myalgia. Material and Methods: 70 male patients with chronic non-bacterial prostatitis and pelvic floor tension myalgia, were divided into two groups. Group (A) received the perineal high voltage tiny impulses electrical stimulation of pain gone pen (PGP) plus the traditional physical therapy. Group (B) received the traditional physical therapy only, PGP stimulation was applied (for a brief period) one (10 clicks) in about 10 minutes on the exaggerated perineal trigger points between anus and scrotum, 3 times weekly for 3 months as a total period of treatment. Methods of assessment (Measurement of the serum cortisol level and the vasual analouge scale). Results: Result showed that PGP was effective and bene-ficial in improving the chronic non-bacterial prostatitis and pelvic floor tension myalgia as evidenced by the highly significant decrease in the serum cortisol level and the visual analouge scale. Conclusion: PGP was effective and beneficial in improving the chronic non-bacterial prostatitis and pelvic floor tension myalgia as evidenced by the highly significant decrease in the serum cortisol level and the visual analouge scale.