Abstract Background: The spine is one of the essential structures in the human body, and it is the third most common site of abnormal cell proliferation, therefore, prompt evaluation and appropriate management of spinal pain and dysfunction is important. Spinal tumors may cause a variety of symptoms depending on their type, location, and rate of growth. Verte-broplasty is a minimally invasive, radiologically guided procedure that consist of percutaneous injection of a surgical cement into a vertebral body. Aim of Study: To evaluate the role of vertebroplasty in management of o vertebral compression fractures in spine tumors. Patients and Methods: In this study a total of 20 patients with 49 vertebral compression fractures underwent vertebro-plasty at our institution andanalysing the clinical and radio-graphic outcomes using the VAS and the DOI scores. Results: Were decreasing in VAS score from 8.65 to 1.8, and ODI score was 84.2, decreasing to 17.4 at the last follow-up visit. Conclusion: Our study demonstrates that PV is a successful technique for painmanagement and consolidation of pathologic vertebral bodies leads to substantial functional improvement with a very low rate of complications.