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Comparison of Visual Outcomes after Two Techniques of Lenticule Extraction in Small Incision Lenticule Extraction

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Last updated: 01 Jan 2025

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Abstract

Abstract Background: Surgical treatment modalities for refractive errors include Laser Assisted In-situ Keratomileusis (LASIK), radial keratotomy, intrastromal corneal ring segments, lenticular extraction, etc. Later, Femtosecond Lenticule Extraction (FLEx) was designed for the treatment of severe myopic patients. With the arrival of the Visumax femtosecond laser and technique refinement by creating 2-3 mm small incisions, small incision lenticule extraction (SMILE) became an in-creasingly popular refractive surgery, which was approved in 2012 by the food and drug administration (FDA), and since then there have been numerous international research were conducted on determining its efficacy and visual outcomes. Aim of Study: To evaluate the effectiveness of two different approaches to the SMILE technique (traditional verses lenti-culerrhexis) in myopic patients. Material and Methods: This study included 60 eyes (n=31 patients) that underwent SMILE for correction of myopia between July 2016 and July 2019. The subjects' eyes were randomly divided into two groups of 30 eyes. Group A eyes underwent lenticulerrhexis (CCL), and group B underwent the conventional myopic correction procedure. A comprehen-sive preoperative examination was done for all subjects, which included slit lamp examination, Pentacam imaging, measuring intraocular pressure (IOP), and uncorrected/corrected distance visual acuity measurements were recorded. Postoperative follow-up was performed on day one and three-months. Primary Outcomes included Bowman's layer micro-distortions and contrast and sensitivity test, while secondary outcomes included corrected and uncorrected distance visual acuity, lenticule extraction duration, manifest refraction, and adverse events. Results: No significance (p=0.52) was demonstrated between group A and B regarding mean pre-operative spherical equivalent (SE), the SE was –4.75 for group A and –4.78 in group B. Bowman's Layer distortions were 3.73, 6.6, and 3.00, 4.73 in group A and B at day one and three-months postoperatively, respectively (p=0.06). Mean contrast and sensitivity was 281, 277, and 317, 320 in groups A and B respectively, at day one and three-months postoperatively, respectively (p=0.38, p=0.52 - Day one and three months postop.). A UDVA of 0.8 or better was demonstrated in 96.7% (29 of 30) for group A and 86.7% (26 of 30) of group B, and no difference between both groups (p=0.16). Sphere equiva-lence mean was –0.16 diopters for group A and –0.27 diopters for group B (p=0.41). The mean length of time of lenticule extraction was 78.4 seconds (range: 59.5 to 124.5 seconds) in group A and 74.3 seconds (range: 52 to 102 seconds) in the conventional group. Conclusion: The CCL technique is an excellent, repro-ducible, less manipulative, and efficient technique of SMILE surgery, that may result in better early corneal healing and visual outcomes compared to the conventional SMILE tech-nique. It is a promising technique that deserve further research and evaluation.

DOI

10.21608/mjcu.2023.305919

Keywords

Myopia, Small incision lenticule extraction, Bowman's layer micro-distortions, Contrast and Sensitivity

Authors

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RAMY R. FIKRY, M.D.;

Last Name

AHMED G. ISHAAK, M.D.

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MOHSEN E. SALEM, M.D;

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AHMED HASSANEIN, M.D.

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Affiliation

The Department of Ophthalmology, Faculty of Medicine, Cairo University

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Volume

91

Article Issue

03

Related Issue

42152

Issue Date

2023-03-01

Receive Date

2023-07-01

Publish Date

2023-03-01

Page Start

65

Page End

73

Print ISSN

0045-3803

Online ISSN

2536-9806

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https://mjcu.journals.ekb.eg/article_305919.html

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https://mjcu.journals.ekb.eg/service?article_code=305919

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305,919

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Original Article

Type Code

263

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Journal

Publication Title

The Medical Journal of Cairo University

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https://mjcu.journals.ekb.eg/

MainTitle

Comparison of Visual Outcomes after Two Techniques of Lenticule Extraction in Small Incision Lenticule Extraction

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Article

Created At

30 Dec 2024