Abstract Background: The Coronavirus Disease 2019 (Covid 19) pandemic has become a significant challenge for the healthcare sector, with a high rate of morbidity and mortality. Co-morbid conditions like diabetes put the patients at higher risk for serious illness and complications. Aim of Study: The current study aimed to use the CT chest severity score to assess the severity of lung affection caused by Covid-19 in diabetic and nondiabetic patients. Patients and Methods: From January to June 2021, high resolution non-contrast Computed Tomography (CT) chest imaging was performed on a total of 120 patients. The com-puted tomography severity score (CTSS) was calculated after analysis of the images. The patients were grouped into mild and severe cases in both diabetic and nondiabetic groups. Results: Among 120 confirmed cases of COVID-19 in-fection, 67 (55.8%) were diabetics and 53 (44.2%) were non-diabetics. Many CT chest findings were observed, including ground glass opacitiesand consolidations. CT chest severity scoring (CTSS) was calculated for each patient. The severe cases (CTSS >18) compromised 43.3% of diabetic patients and 26.4% of non-diabetic group. It was noticed that lower lobes are significantly more affected than upper lobe units on both sides and the posterior basal segments are the most frequently involved segments. Conclusion: According to this study, COVID-19 patients with diabetes comorbidity are at greater risk of severe disease than those without diabetes. Therefore, Clinicians need to focus more on treating COVID-19 pneumonia patients who also have diabetes.