Silver and gold have long been utilized as currency; they have also been used for clinical instruments for their antibacterial properties, which occur in metallic and salt structures. The utilization of metallic nanoparticles for restorative and sterile applications has become more acceptable recently because of advances in nanoscience and nanotechnology. Expanding the utilization of metallic nanoparticles in human well-being is an essential issue. As a general rule, the potential harmfulness of metallic nanoparticles requires safe application tactics. Nanocomposites are an excellent solution since the flexibility of the nano-objects is limited, but their mobility is maintained. This review aims to enhance the current understanding of the effectiveness of nanomaterials in eliminating dangerous bacterial species, improving human health and eliminating many diseases that may appear in the future. These materials will significantly and effectively reduce the future spread of diseases caused by the main bacteria that are resistant to traditional antibiotic treatments.