362111

A report of four patients with Moebius syndrome: New oral anomalies and challenges in dental management

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Last updated: 05 Jan 2025

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Abstract

Background
Moebius syndrome (MBS MIM # 157900) is mostly a sporadic disorder characterized by nonprogressive congenital facial and eye abduction paresis. Some patients have associated limb anomalies. Orofacial abnormalities are regularly associated with the syndrome.
Aim
The authors report four unrelated Egyptian patients with MBS presented with variable oral and dental abnormalities. New orodental findings of the syndrome were presented.
Materials and methods
Dental management was offered to the needed patient with suitable modifications to fit the case. The four probands were subjected to full medical history taking and extensive clinical and orodental examinations. Restorative and prosthetic management with special modifications was highly recommended.
Results
Results exhibited commonly detected orodental anomalies. Alveolar ridge asymmetry, microdontia, and premature eruption were new findings of the syndrome. Increasingly, dental management improved speech, mastication, and esthetic of the patient.
Conclusion
The detection of new oral findings could expand the phenotype of the syndrome. The appropriate recognition of the disorder provides accurate management and patient satisfactory parameters. The authors noted a positive correlation between severity of orodental anomalies and limb involvement. The authors recommend further orodental evaluation of more patients with MBS, which may help in understanding its etiopathological aspects in correlation with its phenotypic diversity.

DOI

10.4103/MXE.MXE_15_19

Keywords

dental management, Facial Palsy, Moebius syndrome, oral anomalies

Authors

First Name

Nehal F.

Last Name

Hassib

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First Name

Mohamed A.

Last Name

AbdelKader

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Email

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Orcid

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First Name

Eman A.

Last Name

AbulEzz

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Orcid

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First Name

Mona S.

Last Name

Aglan

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First Name

Samia A.

Last Name

Temtamy

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Orcid

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Volume

8

Article Issue

2

Related Issue

48654

Issue Date

2020-07-01

Receive Date

2019-09-27

Publish Date

2020-07-11

Print ISSN

2090-8571

Online ISSN

2090-763X

Link

https://mxe.journals.ekb.eg/article_362111.html

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https://mxe.journals.ekb.eg/service?article_code=362111

Order

362,111

Publication Type

Journal

Publication Title

Middle East Journal of Medical Genetics

Publication Link

https://mxe.journals.ekb.eg/

MainTitle

A report of four patients with Moebius syndrome: New oral anomalies and challenges in dental management

Details

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Article

Created At

29 Dec 2024